Document Detail

Endometrial cancer in women 45 years of age or younger.
MedLine Citation:
PMID:  10949386     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: The clinical characteristics and outcomes of endometrial cancer in women 45 years of age or younger evaluated and treated at the community hospital level are presented. METHODS: A series of 500 consecutive women with endometrial cancer operated on by the author over a nine-year period of time was used to identify women 45 years of age or younger and compared to older patients from the author's data base. RESULTS: Although the majority of patients presented with clinical stage I disease, 30% of women 45 years of age or younger had occult metastatic disease and 5.0% had clear cell or papillary serous histology, similar to the older patient population. In addition, survival was similar in both groups of patients. Serum CA-125 was useful in identifying patients with possible occult metastatic disease in the group of women 45 years old or younger. CONCLUSION: Patients 45 years of age or younger with uterine cancer are not ipso facto a "lower risk" group of patients; efforts to preserve fertility should be balanced against a thorough effort to identify those individuals at higher risk for occult metastases.
B Patsner
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  European journal of gynaecological oncology     Volume:  21     ISSN:  0392-2936     ISO Abbreviation:  Eur. J. Gynaecol. Oncol.     Publication Date:  2000  
Date Detail:
Created Date:  2000-12-07     Completed Date:  2000-12-07     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8100357     Medline TA:  Eur J Gynaecol Oncol     Country:  ITALY    
Other Details:
Languages:  eng     Pagination:  249-50     Citation Subset:  IM    
New Jersey Gynecologic Oncology, PA., Little Silver, USA.
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MeSH Terms
CA-125 Antigen / blood
Endometrial Neoplasms / blood,  pathology*
Middle Aged
Neoplasm Staging
Reg. No./Substance:
0/CA-125 Antigen

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