Document Detail

Endometrial Preparation With Estradiol Plus Dienogest (Qlaira) for Office Hysteroscopic Polypectomy: Randomized Pilot Study.
MedLine Citation:
PMID:  22322156     Owner:  NLM     Status:  Publisher    
STUDY OBJECTIVE: To estimate the effectiveness of Qlaira for endometrial preparation in women undergoing hysteroscopic polypectomy in the office setting. DESIGN: Randomized clinical pilot study (Canadian Task Force classification II-2). SETTING: Academic research environment. PATIENTS: Seventy-four cycling women undergoing hysteroscopic polypectomy (polyp size <1.5 cm). INTERVENTIONS: Women were randomized to be operated on during the proliferative phase (cycle day 5-7) of a spontaneous cycle (group A) or after 9 to 11 days of Qlaira intake (group B). Polypectomy was performed by using forceps and bipolar electrodes when required. MEASUREMENTS AND MAIN RESULTS: The quality of visualization of the uterine cavity during the procedure (visual analog score [VAS] 0-5, bad to optimal), total surgeon satisfaction (VAS 0-5, very difficult to easy to perform), and total patient satisfaction (VAS 0-5, severe pain to no pain) were compared. Endometrial thickness before and at the end of the procedure was significantly less in women in group B. Mean duration of interventions was shorter in group B than in group A. In addition, vision quality, and surgeon and patient satisfaction rates were significantly higher in women in group B. CONCLUSIONS: At 10 days before surgery, administration of Qlaira is effective for preparation of the endometrium for hysteroscopic polypectomy in the office setting. With preoperative administration of Qlaira, the surgical procedure can be performed more easily and faster, and both surgeon and patient satisfaction rates are improved.
Ettore Cicinelli; Vincenzo Pinto; Paola Quattromini; Maria Rosa Fucci; Achiropita Lepera; Paola Carmela Mitola; Maria Vittoria Cicinelli; Fusco Annarita; Raffaele Tinelli
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-2-7
Journal Detail:
Title:  Journal of minimally invasive gynecology     Volume:  -     ISSN:  1553-4669     ISO Abbreviation:  -     Publication Date:  2012 Feb 
Date Detail:
Created Date:  2012-2-10     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101235322     Medline TA:  J Minim Invasive Gynecol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2012 AAGL. Published by Elsevier Inc. All rights reserved.
Department of Obstetrics and Gynecology, University of Bari, Bari, Italy (Drs. E. Cicinelli, Pinto, Quattromini, Fucci, Lepera, Carmela, and Tinelli); Faculty of Medicine, University Medical School "San Raffaele," Milano, Italy (Dr. V. Cicinelli); and Department of Public Health, University Medical School of Bari, Bari, Italy (Dr. Annarita).
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