| Endogenous opioids interact in stress-induced hyperglycemia in mice. | |
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MedLine Citation:
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PMID: 6281826 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Intermittent inescapable foot shock stress for 1 hour elicited significant hyperglycemia in mice. Pretreatment with the long acting narcotic antagonist naltrexone (1.0 mg/kg, 1 hr prior to stress) prevented stress hyperglycemia. Naltrexone did not affect blood glucose in unstressed control mice. These findings suggest the involvement of endogenous opioids in the hyperglycemic response to stress in mice. The possible mode of interaction of endorphin in stress hyperglycemia is discussed. |
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Authors:
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S Amir; M Bernstein |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Physiology & behavior Volume: 28 ISSN: 0031-9384 ISO Abbreviation: Physiol. Behav. Publication Date: 1982 Mar |
Date Detail:
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Created Date: 1982-07-22 Completed Date: 1982-07-22 Revised Date: 2008-11-21 |
Medline Journal Info:
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Nlm Unique ID: 0151504 Medline TA: Physiol Behav Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 575-7 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Blood Glucose / analysis Endorphins / metabolism* Hyperglycemia / etiology*, prevention & control Male Mice Mice, Inbred BALB C Naltrexone / pharmacology Stress, Physiological / complications* beta-Endorphin |
| Chemical | |
Reg. No./Substance:
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0/Blood Glucose; 0/Endorphins; 16590-41-3/Naltrexone; 60617-12-1/beta-Endorphin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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