Document Detail


Endogenous occurrence of some anabolic steroids in swine matrices.
MedLine Citation:
PMID:  16192067     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Following findings of 17beta-19-nortestosterone (150-200 microg kg(-1)) in pigs of unspecified gender imported into the European Union, a study to determine steroid and hormone levels in swine from six age/gender categories (uncastrated 'old' boars, cryptorchids, one intersex, barrows, gilts and sows) was initiated. Indeed, for some hormones there has been a discussion about their being endo- or exogenous. Tissue and urine samples from swine from each of the six categories were obtained in Belgium, France, the Netherlands and the USA. Samples were analysed in three laboratories. Quantitation was obtained for norandrostenedione, 19-nortestosterone and boldenone. The results give a well-documented overview of the status of the presence of these hormones in swine. The data illustrate that uncastrated 'old' boars produce the highest percentage of 'positive' matrices, followed by the cryptorchids. Concentrations in the matrices of the barrows and the gilts are lower. Also, sow matrices contain low amounts of nor-steroids. Furthermore, urine samples from an intersex pig contains a higher concentration of nortestosterone than sows and can therefore be suspected for illegal use of these hormones. Veterinarians taking samples in pig farms for the analysis of hormones need to be aware of the presence and concentrations of these substances in the different categories.
Authors:
S Poelmans; K De Wasch; H Noppe; N Van Hoof; S Van Cruchten; B Le Bizec; Y Deceuninck; S Sterk; H J Van Rossum; M K Hoffman; H F De Brabander
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Publication Detail:
Type:  Journal Article; Multicenter Study    
Journal Detail:
Title:  Food additives and contaminants     Volume:  22     ISSN:  0265-203X     ISO Abbreviation:  Food Addit Contam     Publication Date:  2005 Sep 
Date Detail:
Created Date:  2005-09-29     Completed Date:  2006-01-31     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8500474     Medline TA:  Food Addit Contam     Country:  England    
Other Details:
Languages:  eng     Pagination:  808-15     Citation Subset:  IM    
Affiliation:
Laboratory of Chemical Analysis, Research Group of Veterinary Public Health and Zoonoses, Department of Veterinary Public Health and Food Safety, Salisburylaan, 133 B-9820 Merelbeke, Belgium.
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MeSH Terms
Descriptor/Qualifier:
Androstenedione / analogs & derivatives,  analysis
Animals
Drug Residues / analysis
Female
Food Contamination / analysis
Gas Chromatography-Mass Spectrometry / methods,  veterinary
Gonadal Steroid Hormones / analysis*
Male
Meat / analysis
Nandrolone / analysis
Orchiectomy / veterinary
Substance Abuse Detection / methods,  veterinary
Swine / metabolism*
Testosterone / analogs & derivatives,  analysis
Tissue Distribution
Chemical
Reg. No./Substance:
0/Gonadal Steroid Hormones; 434-22-0/Nandrolone; 58-22-0/Testosterone; 63-05-8/Androstenedione; 734-32-7/19-norandrostenedione; 846-48-0/dehydrotestosterone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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