| Endogenous hyperandrogenism and exercise capacity lessons from the exercise-congenital adrenal hyperplasia model. | |
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MedLine Citation:
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PMID: 21714454 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
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Athletic excellence requires a combination of genetic endowment, continuous training, appropriate equipment, and proper nutrition. However, the specific genetic and/or intrinsic hormonal milieus that contribute to athletic performance are not clearly understood. Androgens are thought to play an important role in exercise-induced target tissue response. In adults, the use of exogenous anabolic steroids was found to improve athletic performance, decrease fatigue, increase muscle mass, and increase aggressiveness. However, the benefit of these substances in adolescents remains questionable. Moreover, the role of endogenous androgen secretion for competitive performance success is far less studied. The present review will summarize aspects related to the effect of endogenous hyperandrogenism on exercise performance, as seen in polycystic ovary syndrome (PCOS), and will concentrate on important lessons learned from the unique model of exercise in congenital adrenal hyperplasia, a disease associated with endogenous hyperandrogenism. |
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Authors:
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Alon Eliakim; Dan Nemet |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Journal of pediatric endocrinology & metabolism : JPEM Volume: 23 ISSN: 0334-018X ISO Abbreviation: J. Pediatr. Endocrinol. Metab. Publication Date: 2010 Dec |
Date Detail:
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Created Date: 2011-06-30 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9508900 Medline TA: J Pediatr Endocrinol Metab Country: England |
Other Details:
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Languages: eng Pagination: 1213-9 Citation Subset: IM |
Affiliation:
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Child Health & Sports Center, Pediatric Department, Meir Medical Center, Sackler School of Medicine, Tel-Aviv University, Kfar-Saba, Israel. Eliakim.alon@clalit.org.il |
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