Document Detail

Endogenous fatty acid synthesis in squamous cell carcinomas of the oral cavity.
MedLine Citation:
PMID:  11010783     Owner:  NLM     Status:  MEDLINE    
We measured the synthesis of endogenous fatty acids in oral squamous cell carcinoma, its adjacent tissue, and normal oral tissues that were collected fresh from surgical specimens. The tissues were minced in Roswell Park Memorial Institute Medium 1640 (RPMI 1640) and incubated in [1(2)-(14)C] acetic acid, sodium salt ((14)CH(3)(14)CO(2)Na). Total lipids were then extracted and(14)C was measured by scintillation counter. We found that incorporation of(14)C in the total lipids of squamous cell carcinoma was significantly higher than in the other tissues.
C B Guo; L H Cui; G Y Yu; D X Liu; S C Meng; Q Song
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  The British journal of oral & maxillofacial surgery     Volume:  38     ISSN:  0266-4356     ISO Abbreviation:  Br J Oral Maxillofac Surg     Publication Date:  2000 Oct 
Date Detail:
Created Date:  2001-02-08     Completed Date:  2001-02-08     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8405235     Medline TA:  Br J Oral Maxillofac Surg     Country:  SCOTLAND    
Other Details:
Languages:  eng     Pagination:  506-8     Citation Subset:  D; IM    
Copyright Information:
Copyright 2000 The British Association of Oral and Maxillofacial Surgeons.
Department of Oral and Maxillofacial Surgery, School of Stomatology, Beijing Medical University, Beijing, People's Republic of China.
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MeSH Terms
Carbon Radioisotopes
Carcinoma, Squamous Cell / chemistry,  metabolism*
Fatty Acids / analysis,  biosynthesis*
Mouth Mucosa / chemistry,  metabolism
Mouth Neoplasms / chemistry,  metabolism*
Scintillation Counting
Reg. No./Substance:
0/Carbon Radioisotopes; 0/Fatty Acids

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