| Endogenous carbon monoxide production: a rare and detrimental complication of extracorporeal membrane oxygenation. | |
| | |
MedLine Citation:
|
PMID: 19033779 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Extracorporeal membrane oxygenation (ECMO) is a technique that can support gas-exchange and cardiac function in patients with acute respiratory or cardiac failure that is not responsive to conservative treatment. ECMO is a high-risk procedure in critically ill patients and both technical and patient-related complications frequently occur. We report on a patient with end-stage pulmonary fibrosis (histiocytosis x), in whom ECMO was used as bridge to urgent lung transplantation. Respiratory insufficiency necessitating ECMO therapy was due to spontaneous pneumothorax with bronchopleural fistula. Access was initially made by femoral veno-venous canulation. Due to right heart failure, access was switched to veno-arterial using the two existing canulae as efferent system and implanting a third canula on the femoral artery using a graft. Despite marked hemodynamic improvement after this intervention, high flow rates creating high premembrane pressures were required to ensure oxygenation. High levels of carboxyhemoglobin (COHb) occurred, most likely due to massive mechanical hemolysis in the ECMO circuit. This may have had detrimental effects by further complicating tissue oxygenation. We recommend that COHb should routinely be checked in ECMO patients. |
| | |
Authors:
|
Greet Hermans; Alexander Wilmer; Daniel Knockaert; Bart Meyns |
Related Documents
:
|
4064719 - Continuous, on-line, real-time measurement of cardiac output and derived cardiorespirat... 3966669 - Errors in measurement of oxygen uptake due to anesthetic gases. 1112119 - Prolonged rate of decay of arterial po2 following oxygen breathing in chronic airways o... 880179 - Theoretical analysis of altitude tolerance and hemoglobin function. 3174409 - Energy cost of walking with flat feet. 10552119 - Hemodynamic patterns of survivors and nonsurvivors during high risk elective surgical o... 9272429 - Immunoelectron microscopic study of the luminal release of serotonin from rat enterochr... 2316319 - Preoxygenation of patients for coronary artery bypass grafting: vital capacity versus t... 12779209 - Pseudotumour cerebri, csf rhinorrhoea and the role of venous sinus stenting in treatment. |
Publication Detail:
|
Type: Case Reports; Journal Article |
Journal Detail:
|
Title: ASAIO journal (American Society for Artificial Internal Organs : 1992) Volume: 54 ISSN: 1538-943X ISO Abbreviation: ASAIO J. Publication Date: 2008 Nov-Dec |
Date Detail:
|
Created Date: 2008-11-26 Completed Date: 2009-02-09 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 9204109 Medline TA: ASAIO J Country: United States |
Other Details:
|
Languages: eng Pagination: 633-5 Citation Subset: IM |
Affiliation:
|
Department of General Internal Medicine, Medical Intensive Care Unit, University Hospitals, Leuven, Belgium. Greet.Hermans@uz.kuleuven.ac.be |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adult Carbon Monoxide / blood* Carboxyhemoglobin / biosynthesis Extracorporeal Membrane Oxygenation / adverse effects* Humans Male Pulmonary Fibrosis / surgery |
| Chemical | |
Reg. No./Substance:
|
630-08-0/Carbon Monoxide; 9061-29-4/Carboxyhemoglobin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Fabrication of biomatrix/polymer hybrid scaffold for heart valve tissue engineering in vitro.
Next Document: Usefulness of PET/CT for detecting a second primary cancer after treatment for squamous cell carcino...