Document Detail

Endogenous anabolic hormonal and growth factor responses to heavy resistance exercise in males and females.
MedLine Citation:
PMID:  1860749     Owner:  NLM     Status:  MEDLINE    
To examine endogenous anabolic hormonal responses to two different types of heavy resistance exercise protocols (HREPs), eight male and eight female subjects performed two randomly assigned protocols (i.e. P-1 and P-2) on separate days. Each protocol consisted of eight identically ordered exercises carefully designed to control for load, rest period length, and total work (J) effects. P-1 utilized a 5 RM load, 3-min rest periods and had lower total work than P-2. P-2 utilized a 10 RM load, 1-min rest periods and had a higher total work than P-1. Whole blood lactate and serum glucose, human growth hormone (hGH), testosterone (T), and somatomedin-C [SM-C] (i.e. insulin-like growth factor 1, IGF-1) were determined pre-exercise, mid-exercise (i.e. after 4 of the 8 exercises), and at 0, 5, 15, 30, and 60 min post-exercise. Males demonstrated significant (p less than 0.05) increases above rest in serum T values, and all serum concentrations were greater than corresponding female values. Growth hormone increases in both males and females following the P-2 HREP were significantly greater at all time points than corresponding P-1 values. Females exhibited significantly higher pre-exercise hGH levels compared to males. The P-1 exercise protocol did not result in any hGH increases in females. SM-C demonstrated random significant increases above rest in both males and females in response to both HREPs.(ABSTRACT TRUNCATED AT 250 WORDS)
W J Kraemer; S E Gordon; S J Fleck; L J Marchitelli; R Mello; J E Dziados; K Friedl; E Harman; C Maresh; A C Fry
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Publication Detail:
Type:  Clinical Trial; Journal Article; Randomized Controlled Trial    
Journal Detail:
Title:  International journal of sports medicine     Volume:  12     ISSN:  0172-4622     ISO Abbreviation:  Int J Sports Med     Publication Date:  1991 Apr 
Date Detail:
Created Date:  1991-09-04     Completed Date:  1991-09-04     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8008349     Medline TA:  Int J Sports Med     Country:  GERMANY    
Other Details:
Languages:  eng     Pagination:  228-35     Citation Subset:  IM    
Exercise Physiology Division, U.S. Army Research Institute of Environmental Medicine, Natick, MA 01760-5007.
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MeSH Terms
Adaptation, Physiological
Analysis of Variance
Exercise / physiology*
Growth Hormone / blood*
Lactates / blood
Lactic Acid
Sex Factors
Somatomedins / metabolism*
Testosterone / blood
Reg. No./Substance:
0/Lactates; 0/Somatomedins; 50-21-5/Lactic Acid; 58-22-0/Testosterone; 9002-72-6/Growth Hormone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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