Document Detail


Endocrinology of pregnancy in the dog: a review.
MedLine Citation:
PMID:  18556055     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Pregnancy regulation in the dog is not yet fully elucidated. Since plasma progesterone concentrations are similar in pregnant versus non-pregnant animals, it is a poor reflection on CL function and progesterone metabolism. Increased progesterone secretion by the CL in pregnant animals follows implantation and relaxin secretion by the feto-placental units. Progesterone is absolutely required to maintain pregnancy and no placental sources of progesterone have been identified. Pregnancy can be artificially maintained by progesterone administration. Prolactin secretion appears to be increased in response to the increase in relaxin production and occurs independent of estrogen production by the CL. The respective roles of LH, FSH and prolactin are still unclear, with considerable conflicting evidence among studies. However, it appears that prolactin is absolutely required, whereas LH is either permissive or facilitates CL function during pregnancy. Pre-implantation events are still poorly defined in the bitch, and no embryonic factors have been isolated or purified, preventing early pregnancy diagnosis. Parturition occurs following luteolysis, which results from the release of prostaglandin F(2alpha), which begins 36h prepartum in a process similar to that observed in other species. The role of estrogens at the time of parturition remains undefined.
Authors:
K Verstegen-Onclin; J Verstegen
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Publication Detail:
Type:  Journal Article; Review     Date:  2008-06-16
Journal Detail:
Title:  Theriogenology     Volume:  70     ISSN:  0093-691X     ISO Abbreviation:  Theriogenology     Publication Date:  2008 Aug 
Date Detail:
Created Date:  2008-06-30     Completed Date:  2008-10-31     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0421510     Medline TA:  Theriogenology     Country:  United States    
Other Details:
Languages:  eng     Pagination:  291-9     Citation Subset:  IM    
Affiliation:
Large Animal Clinical Sciences, Small Animal Reproduction Center, College of Veterinary Medicine, University of Florida, 2015 SW 16th Avenue, Gainesville, FL 32610-0136, USA. onclink@vetmed.ufl.edu
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MeSH Terms
Descriptor/Qualifier:
Animals
Dogs / physiology*
Endocrinology*
Female
Pregnancy
Pregnancy, Animal / physiology*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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