Document Detail


Endocrinology of anorexia of ageing.
MedLine Citation:
PMID:  15261848     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Appetite and food intake decrease with normal ageing, predisposing to the development of under-nutrition. Under-nutrition is common in older people and has been implicated in the development and progression of chronic diseases commonly affecting the elderly, as well as in increasing mortality. An understanding of the factors that contribute to the physiological and pathological declines in food intake in older people is likely to aid in the development of effective forms of prevention and treatment. Ageing affects many of the endocrine factors involved in the control of appetite and feeding but few studies have been performed in humans to clarify these changes. Possible hormonal causes of the anorexia of ageing include increased activity of cholecystokinin, leptin and various cytokines and reduced activity of ghrelin and testosterone.
Authors:
Ian McPhee Chapman
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Best practice & research. Clinical endocrinology & metabolism     Volume:  18     ISSN:  1521-690X     ISO Abbreviation:  Best Pract. Res. Clin. Endocrinol. Metab.     Publication Date:  2004 Sep 
Date Detail:
Created Date:  2004-07-20     Completed Date:  2005-01-18     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  101120682     Medline TA:  Best Pract Res Clin Endocrinol Metab     Country:  England    
Other Details:
Languages:  eng     Pagination:  437-52     Citation Subset:  IM    
Copyright Information:
Copyright 2004 Elsevier Ltd.
Affiliation:
University of Adelaide Department of Medicine, Royal Adelaide Hospital, North Terrace, Adelaide, SA 5000, Australia. ian.chapman@adelaide.edu.au
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MeSH Terms
Descriptor/Qualifier:
Aged
Aging / physiology*
Androgens / physiology
Animals
Anorexia*
Appetite Regulation
Cholecystokinin / physiology
Cytokines / physiology
Ghrelin
Hormones / physiology*
Humans
Leptin / physiology
Neurotransmitter Agents / physiology
Peptide Hormones / physiology
Protein-Energy Malnutrition / epidemiology
Chemical
Reg. No./Substance:
0/Androgens; 0/Cytokines; 0/Ghrelin; 0/Hormones; 0/Leptin; 0/Neurotransmitter Agents; 0/Peptide Hormones; 9011-97-6/Cholecystokinin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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