Document Detail

Endocrine tests in phenotypic children with bilateral impalpable testes can reliably predict "congenital" anorchism.
MedLine Citation:
PMID:  23600     Owner:  NLM     Status:  MEDLINE    
Congenital anorchism is a rare condition. Bilateral impa-pable undescended testes are relatively common by comparison. Surgical exploration has been regarded as the final arbiter between anorchism and bilateral cryptorchism. Exploration has not proved completely reliable in making this differentiation. Endocrine studies, particularly the human chorionic gonadotropin (HCG) stimulation test together with measurements of basal plasma gonadotropins, can reliably exclude "functioning" testicular tissue. Eleven fully evaluated and operated cases support this contention. In the specific clinical setting of a normal phenotypic male child with a 46XY karyotype and no müllerian structures palpable on rectal examination, nonfunctioning testes on endocrine testing means congenital anorchism and surgical confirmation is unnecessary. In contradistinction, a positive HCG test would appear to mandate through and extensive surgical exploration.
S B Levitt; S J Kogan; K M Schneider; J M Becker; E H Sobel; R H Mortimer; R M Engel
Publication Detail:
Type:  Case Reports; Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Urology     Volume:  11     ISSN:  0090-4295     ISO Abbreviation:  Urology     Publication Date:  1978 Jan 
Date Detail:
Created Date:  1978-03-10     Completed Date:  1978-03-10     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0366151     Medline TA:  Urology     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  11-7     Citation Subset:  IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Child, Preschool
Chorionic Gonadotropin / diagnostic use
Cryptorchidism / diagnosis*
Diagnosis, Differential
Follicle Stimulating Hormone / blood
Functional Laterality
Gonadotropin-Releasing Hormone / diagnostic use
Luteinizing Hormone / blood
Testis / abnormalities*
Testosterone / blood
Reg. No./Substance:
0/Chorionic Gonadotropin; 33515-09-2/Gonadotropin-Releasing Hormone; 58-22-0/Testosterone; 9002-67-9/Luteinizing Hormone; 9002-68-0/Follicle Stimulating Hormone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Uric acid calculi: results of conservative treatment.
Next Document:  Acid-base indices in ovine blood and cerebrospinal fluid