| Endocrine oncology in pregnancy. | |
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MedLine Citation:
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PMID: 22115166 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Endocrine tumours occur rarely in pregnant women but present clinicians with unique challenges. A high index of suspicion is often required to make a diagnosis since the symptoms and signs associated with many of these tumours, including insulinoma, adrenocortical carcinoma and phaeochromocytoma, mimic those of normal pregnancy or its complications, such as pre-eclampsia. The evidence base which informs management is very limited hence decisions on investigation and therapy must be individualised and undertaken jointly by the multidisciplinary medical team and the patient. The optimal strategy will depend on the nature and stage of the endocrine tumour, gestational stage, treatments available and patient wishes. Thus, surgical intervention, appropriately timed, may be considered in pregnancy for resectable adrenocortical carcinoma or phaeochromocytoma, but delayed until the postpartum period for well-differentiated thyroid cancer. Medical therapy may be required to reduce the drive to tumour growth, control symptoms of hormone excess and to minimise the risks of surgery, anaesthesia or labour. |
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Authors:
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A Lansdown; D A Rees |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Best practice & research. Clinical endocrinology & metabolism Volume: 25 ISSN: 1532-1908 ISO Abbreviation: Best Pract. Res. Clin. Endocrinol. Metab. Publication Date: 2011 Dec |
Date Detail:
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Created Date: 2011-11-25 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101120682 Medline TA: Best Pract Res Clin Endocrinol Metab Country: Netherlands |
Other Details:
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Languages: eng Pagination: 911-26 Citation Subset: IM |
Copyright Information:
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Copyright © 2011 Elsevier Ltd. All rights reserved. |
Affiliation:
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Centre for Endocrine and Diabetes Sciences, School of Medicine, Cardiff University, Cardiff, UK. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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