| Endocrine mechanisms of blood pressure rhythms. | |
| | |
MedLine Citation:
|
PMID: 8853637 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
The temporal organization of blood pressure is mainly controlled by neuroendocrine mechanisms. The monoaminergic systems appear to integrate the major driving factors of temporal variability, but evidence also indicates a role of the hypothalamic-pituitary-adrenal, hypothalamic-pituitary-thyroid, opioid, renin-angiotensin-aldosterone, and endothelial systems as well as other vasoactive peptides. Although their hormonal secretions are typically episodic, the probability of secretory episodes is "gated" by mechanisms that are coupled either to sleep or to an endogenous pacemaker which usually is predominantly (though not only) circadian. Many hormones with established actions on the cardiovascular system (arginine vasopressin, vasoactive intestinal peptide, melatonin, somatotropin, insulin, steroids, serotonin, CRF, ACTH, TRH, endogenous opioids, and prostaglandin E2) are also involved in sleep induction or arousal. Hence, physical, mental, and pathologic stimuli, which may drive activation or inhibition of these neuroendocrine effectors of biologic rhythmicity, may also interfere with the temporal blood pressure structure. On the other hand, the immediate adaptation of the exogenous components of blood pressure rhythms to the demands of the environment are modulated by the circadian-time-dependent responsiveness of the biologic oscillators and their neuroendocrine effectors. These notions may contribute to a better understanding of the pathophysiology and therapeutics of changes in blood pressure. |
| | |
Authors:
|
F Portaluppi; L Vergnani; R Manfredini; C Fersini |
Related Documents
:
|
16864147 - Effects of raloxifene therapy on plasma renin and aldosterone levels and blood pressure... 18356687 - The antihypertensive effects of quercetin in a salt-sensitive model of hypertension. 15277317 - Effect of aldosterone antagonism on myocardial dysfunction in hypertensive patients wit... 2532027 - Effect of a total artificial heart on adaptive hormonal responses in humans with end-st... 7056197 - Cranial blood flow and blood pressure changes during sleep in the human neonate. 959767 - Effect of barium meal on resting gastro-oesophageal sphincter pressure in normal human ... |
Publication Detail:
|
Type: Journal Article; Review |
Journal Detail:
|
Title: Annals of the New York Academy of Sciences Volume: 783 ISSN: 0077-8923 ISO Abbreviation: Ann. N. Y. Acad. Sci. Publication Date: 1996 Aug |
Date Detail:
|
Created Date: 1996-11-14 Completed Date: 1996-11-14 Revised Date: 2005-11-16 |
Medline Journal Info:
|
Nlm Unique ID: 7506858 Medline TA: Ann N Y Acad Sci Country: UNITED STATES |
Other Details:
|
Languages: eng Pagination: 113-31 Citation Subset: IM |
Affiliation:
|
Hypertension Unit, First and Second Institute of Internal Medicine, University of Ferrara, Italy. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Animals Blood Pressure / physiology* Circadian Rhythm* Hormones / physiology* Humans |
| Chemical | |
Reg. No./Substance:
|
0/Hormones |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Signal transduction in animal models of normotension and hypertension.
Next Document: Relationships of the circadian rhythms of thrombotic, ischemic, hemorrhagic, and arrhythmic events t...