Document Detail

Endocrine control of sheep adipose tissue fatty acid synthesis: depot specific differences in response to lactation.
MedLine Citation:
PMID:  8514241     Owner:  NLM     Status:  MEDLINE    
The effects of lactation and insulin, growth hormone and dexamethasone (a glucocorticoid analogue) have been assessed on the rate of fatty acid synthesis in adipose tissue from omental (abdominal), subcutaneous and popliteal (intermuscular) depots of sheep. Adipocyte mean cell volume was greatest in omental tissue but the rate of fatty acid synthesis was similar in omental and subcutaneous adipose tissue in non-lactating ewes. Insulin increased the rate of fatty acid synthesis in tissue from all three depots and this was antagonised by growth hormone. The effects of growth hormone were less in omental adipose tissue from non-lactating sheep than in the other two depots. Lactation decreased the rate of fatty acid synthesis in all three depots, but to a lesser extent in omental than the other depots. Insulin resistance was apparent in subcutaneous and popliteal tissues from lactating ewes but not in omental tissue. Omental adipose tissue, thus differs in several aspects from the two carcass depots. Differences in response to hormones in omental adipose tissue were apparent in young sheep before the onset of fattening when omental adipocytes are similar in size to subcutaneous adipocytes.
L de la Hoz; R G Vernon
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme     Volume:  25     ISSN:  0018-5043     ISO Abbreviation:  Horm. Metab. Res.     Publication Date:  1993 Apr 
Date Detail:
Created Date:  1993-07-19     Completed Date:  1993-07-19     Revised Date:  2009-02-19    
Medline Journal Info:
Nlm Unique ID:  0177722     Medline TA:  Horm Metab Res     Country:  GERMANY    
Other Details:
Languages:  eng     Pagination:  214-8     Citation Subset:  IM    
Departamento de Higiene y Tecnologia de los Alimentos, Facultad de Veterinaria, Universidad Complutense Madrid, Spain.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Adipose Tissue / metabolism*
Dexamethasone / pharmacology
Endocrine Glands / metabolism*
Fatty Acids / biosynthesis*
Growth Hormone / pharmacology
Insulin / pharmacology
Lactation / physiology*
Reg. No./Substance:
0/Fatty Acids; 11061-68-0/Insulin; 50-02-2/Dexamethasone; 9002-72-6/Growth Hormone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Glucose transport during cell cycle in IM9 lymphocytes.
Next Document:  The effect of chronic nicotine administration on bone mineral content in mice.