Document Detail

Endocrine abnormalities in thalassemia major.
MedLine Citation:
PMID:  433875     Owner:  NLM     Status:  MEDLINE    
Endocrine function evaluations in 16 patients with beta-thalassemia indicate that hypogonadotropic hypogonadism, hypoparathyroidism, and reduced adrenocorticotropic hormone reserve occur frequently, whereas reduced growth hormone and thyroid reserve are less common manifestations. Hemosiderosis-induced damage of the endocrine glands seems to be the main cause for endocrine dysfunction in the patients studied.
G Costin; M D Kogut; C B Hyman; J A Ortega
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  American journal of diseases of children (1960)     Volume:  133     ISSN:  0002-922X     ISO Abbreviation:  Am. J. Dis. Child.     Publication Date:  1979 May 
Date Detail:
Created Date:  1979-06-29     Completed Date:  1979-06-29     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0370471     Medline TA:  Am J Dis Child     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  497-502     Citation Subset:  AIM; IM    
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MeSH Terms
Child, Preschool
Endocrine Glands / pathology,  physiopathology*
Gonads / physiopathology
Liver / pathology
Parathyroid Glands / physiopathology
Pituitary Gland / physiopathology
Pituitary-Adrenal System / physiopathology
Thalassemia / pathology,  physiopathology*
Thyroid Gland / physiopathology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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