| Endocervical curettage after cryotherapy for cervical intraepithelial neoplasia. | |
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MedLine Citation:
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PMID: 4009559 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Two hundred forty-five patients were studied prospectively to determine the value of endocervical curettage (ECC) in the follow-up of patients having undergone cryotherapy for cervical intraepithelial neoplasia (CIN). Patients at high risk of treatment failure were divided into three groups: (I) CIN grade 3 lesions confined strictly to the ectocervix (86 patients), (II) CIN grade 1-3 lesions involving the endocervix to a depth of up to 5 mm and a negative ECC prior to cryotherapy (64 patients), and (III) CIN grade 1-3 lesions confined to the ectocervix or extending into the endocervix to a depth of up to 5 mm and a positive ECC (27 patients). A fourth group, 68 patients with CIN grade 1 and 2 lesions confined to the ectocervix, was considered to be at low risk of treatment failure and served as controls. All the patients had satisfactory colposcopy. ECC was performed at 6 and 12 months after cryotherapy. Recurrent or persistent CIN was diagnosed in 19 of 245 patients (8%) and was found in group I (6 of 86, or 8%), II (6 of 64, or 9%), III (3 of 27, or 11%) and IV (4 of 68, or 6%). The rates of treatment failure did not differ significantly between the various groups (p greater than 0.1). ECC was positive in 4 of 19 (21%) of the cryotherapy failures (group I, 1 of 6; II, 2 of 6; III, 1 of 3; IV, 0 of 4). In two cases of a positive follow-up ECC, cervical cytology was also positive.(ABSTRACT TRUNCATED AT 250 WORDS) |
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Authors:
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H B Krebs; J B Wheelock |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: The Journal of reproductive medicine Volume: 30 ISSN: 0024-7758 ISO Abbreviation: J Reprod Med Publication Date: 1985 May |
Date Detail:
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Created Date: 1985-08-12 Completed Date: 1985-08-12 Revised Date: 2005-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0173343 Medline TA: J Reprod Med Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 379-82 Citation Subset: IM |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Biopsy Carcinoma in Situ / pathology, surgery* Cervix Uteri / pathology Colposcopy Cryosurgery* Curettage* Female Follow-Up Studies Humans Neoplasm Recurrence, Local / pathology Risk Time Factors Uterine Cervical Dysplasia / pathology, surgery* Uterine Cervical Neoplasms / pathology, surgery* Vaginal Smears |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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