Document Detail

Endocarditis associated with antineutrophil cytoplasmic antibodies: a case report and review of the literature.
MedLine Citation:
PMID:  16440133     Owner:  NLM     Status:  MEDLINE    
We report a case of subacute bacterial endocarditis associated with small vessel vasculitis and a strongly positive cytoplasmic antineutrophil cytoplasmic antibody (c-ANCA) test. It is important to recognize this cause of positive c-ANCA because infectious endocarditis may closely mimic the clinical manifestations of ANCA-associated vasculitides such as Wegener granulomatosis or microscopic polyangiitis. Furthermore, ANCA-associated vasculitis may result in noninfectious endocarditis, which may be confused with bacterial endocarditis. In this paper, we review reported cases of ANCA-positive bacterial endocarditis and compare them to the reported cases of ANCA-associated idiopathic vasculitis with endocardial compromise.
Julio A Chirinos; Vicente F Corrales-Medina; Santiago Garcia; Daniel M Lichtstein; Alan L Bisno; Simon Chakko
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Publication Detail:
Type:  Case Reports; Journal Article; Review     Date:  2006-01-27
Journal Detail:
Title:  Clinical rheumatology     Volume:  26     ISSN:  0770-3198     ISO Abbreviation:  Clin. Rheumatol.     Publication Date:  2007 Apr 
Date Detail:
Created Date:  2007-03-02     Completed Date:  2007-06-19     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8211469     Medline TA:  Clin Rheumatol     Country:  Belgium    
Other Details:
Languages:  eng     Pagination:  590-5     Citation Subset:  IM    
Department of Medicine, University of Miami, School of Medicine and Veterans Affairs Medical Center, Miami, FL, USA.
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MeSH Terms
Antibodies, Antineutrophil Cytoplasmic / blood*,  immunology
Aortic Valve / immunology,  microbiology*,  surgery
Endocarditis, Subacute Bacterial / complications,  immunology*,  therapy
Enterococcus faecalis / pathogenicity*
Gram-Positive Bacterial Infections / complications,  microbiology*,  surgery
Middle Aged
Wegener Granulomatosis / immunology
Reg. No./Substance:
0/Antibodies, Antineutrophil Cytoplasmic

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