Document Detail

Endocardial mapping of ventricular tachycardia in one-day-old myocardial infarction.
MedLine Citation:
PMID:  3702039     Owner:  NLM     Status:  MEDLINE    
Endocardial mapping of ventricular tachycardia (VT) was performed in one-day-old myocardial infarction using a matrix electrode (6 X 7 = 42) placed on the endocardial surface of the perfused isolated canine heart. Spontaneous focal VT was observed in all 7 dogs. It was neither affected nor terminated by electrical stimulation. Focal VT was induced in 5 dogs by constant pacing or premature programmed stimulation of the main left bundle. It was terminated by electrical stimulation and induction of the VT was suppressed by verapamil (5 X 10(-7)). Endocardial mapping of the spontaneous focal VT and induced focal VT showed initiation of activation from the surviving Purkinje fiber in the infarcted or border zone with subsequent circular expansion of excitation. Reentrant VT was induced in 3 dogs by bursts of rapid pacing and deteriorated into ventricular fibrillation. Endocardial mapping showed a continuous arc of functional conduction block and slowly circulating activation front around the block. It is suggested that in experimental one-day-old myocardial infarction VT resulted from abnormal automaticity and triggered activity in the surviving Purkinje fiber and reentry in the subendocardial muscle layer.
T Ohta; J Toyama; M Hirai; T Osaka; I Kodama; K Yamada
Related Documents :
7522139 - Electrophysiologic characteristics at initiation of ventricular tachycardia and ventric...
15145109 - Endocardial and epicardial radiofrequency ablation of ventricular tachycardia associate...
17018339 - Twelve-lead ecg features to identify ventricular tachycardia arising from the epicardia...
12439369 - Primary and secondary prevention of sudden cardiac death: the role of the implantable c...
18328339 - Multiple macroreentrant ventricular tachycardias exhibiting centrifugal endocardial act...
20946289 - Spironolactone therapy is associated with reduced ventricular tachycardia rate in patie...
6201299 - Postextrasystolic alterations in refractoriness of the his-purkinje system and ventricu...
18230639 - New two-dimensional global longitudinal strain and strain rate imaging for assessment o...
8121459 - Use of a monoclonal antibody directed against the platelet glycoprotein iib/iiia recept...
Publication Detail:
Type:  In Vitro; Journal Article    
Journal Detail:
Title:  Japanese circulation journal     Volume:  50     ISSN:  0047-1828     ISO Abbreviation:  Jpn. Circ. J.     Publication Date:  1986 Jan 
Date Detail:
Created Date:  1986-06-09     Completed Date:  1986-06-09     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7806868     Medline TA:  Jpn Circ J     Country:  JAPAN    
Other Details:
Languages:  eng     Pagination:  84-90     Citation Subset:  IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Electric Stimulation
Endocardium / physiopathology
Heart Conduction System / physiopathology*
Myocardial Infarction / physiopathology*
Purkinje Fibers / physiopathology
Tachycardia / etiology*
Verapamil / pharmacology
Reg. No./Substance:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Circus movement tachycardia induced by a single premature stimulus on the ventricular sheet--evaluat...
Next Document:  A study on entrainment in various forms of tachycardias.