Document Detail

Endocardial fibroelastosis with coronary artery thromboembolus and myocardial infarction.
MedLine Citation:
PMID:  1934842     Owner:  NLM     Status:  MEDLINE    
We report a case of an 18-month-old male, born to a woman with third trimester febrile illness, who had a history of congestive heart failure and respiratory distress, cardiomegaly, and electrocardiographic (ECG) findings suggestive of cardiomyopathy and myocarditis. After gradual improvement in heart size and function with pharmacologic therapy, he developed a terminal episode of respiratory distress and cardiogenic shock, with ECG findings of an anterolateral infarct. At autopsy it was found that endocardial fibroelastosis with mural thrombi in the left ventricle had been complicated by thromboembolism to the left anterior descending coronary artery, resulting in transmural infarction of the anteroseptal region of the left ventricle. Myocardial infarction is a potential but unusual thromboembolic complication of endocardial fibroelastosis. A high index of suspicion for coronary artery thromboemboli should be maintained in pediatric patients with cardiomyopathy and suspected myocardial infarction.
K L Lane; A J Herzberg; K A Reimer; W D Bradford; S A Schall
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Clinical pediatrics     Volume:  30     ISSN:  0009-9228     ISO Abbreviation:  Clin Pediatr (Phila)     Publication Date:  1991 Oct 
Date Detail:
Created Date:  1991-12-17     Completed Date:  1991-12-17     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0372606     Medline TA:  Clin Pediatr (Phila)     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  593-8     Citation Subset:  AIM; IM    
Department of Pathology, Duke University Medical Center, Durham, North Carolina.
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MeSH Terms
Coronary Thrombosis / etiology*,  pathology,  physiopathology
Endocardial Fibroelastosis / complications*,  pathology,  physiopathology
Heart Ventricles / pathology
Myocardial Infarction / etiology*,  pathology,  physiopathology

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