Document Detail

Endobronchial and parenchymal juvenile laryngotracheobronchial papillomatosis. Effect of photodynamic therapy.
MedLine Citation:
PMID:  1935314     Owner:  NLM     Status:  MEDLINE    
Juvenile laryngotracheobronchial papillomatosis (JLTBP) is a recurrent, prolonged disease usually confined to the upper airway. Rarely, tracheobronchial tree or lung parenchymal involvement occurs. The various therapeutic interventions are often unsuccessful once extralaryngeal involvement becomes apparent. Photodynamic therapy (PDT) has been successful in eradicating JLTBP in a few case reports. We present a case of extensive JLTBP with parenchymal involvement treated with multiple courses of PDT. We demonstrated temporary regression of endobronchial papillomas, but no change in parenchymal lesions. Recurrent endobronchial disease was most likely related to reinfection from parenchymal lesions inaccessible to PDT.
S G Basheda; A C Mehta; G De Boer; J P Orlowski
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Chest     Volume:  100     ISSN:  0012-3692     ISO Abbreviation:  Chest     Publication Date:  1991 Nov 
Date Detail:
Created Date:  1991-12-03     Completed Date:  1991-12-03     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0231335     Medline TA:  Chest     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1458-61     Citation Subset:  AIM; IM    
Department of Pulmonary Disease, Cleveland Clinic Foundation 44195-5038.
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MeSH Terms
Bronchial Neoplasms / therapy*
Laryngeal Neoplasms / therapy*
Neoplasm Recurrence, Local
Papilloma / therapy*
Remission Induction
Tracheal Neoplasms / therapy*

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