Document Detail

Endoarterial treatment of acute ischemia of the limbs with urokinase. Italian Cooperative Study "Bologna".
MedLine Citation:
PMID:  2768959     Owner:  NLM     Status:  MEDLINE    
Authors report the results of the treatment of acute ischemia of the limbs with urokinase in patients included in a polycentric study group called "Bologna". A total of 111 patients affected with acute ischemias of the limbs caused by arterial or graft thromboses were treated with intra-arterial urokinase with a loading dose of 200,000 U.I., followed by 75,000 I.U./hour maintenance dose for 72 hours at the most. With this treatment 83.5% of clinically positive results was obtained. Complications and angiographic results are discussed.
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  International angiology : a journal of the International Union of Angiology     Volume:  8     ISSN:  0392-9590     ISO Abbreviation:  Int Angiol     Publication Date:    1989 Jan-Mar
Date Detail:
Created Date:  1989-10-03     Completed Date:  1989-10-03     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  8402693     Medline TA:  Int Angiol     Country:  ITALY    
Other Details:
Languages:  eng     Pagination:  53-6     Citation Subset:  IM    
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MeSH Terms
Acute Disease
Blood Coagulation
Extremities / blood supply*
Injections, Intra-Arterial
Ischemia / drug therapy*,  physiopathology,  surgery
Urokinase-Type Plasminogen Activator / adverse effects,  therapeutic use*
Reg. No./Substance:
EC Plasminogen Activator

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