Document Detail


Endemic goiter in Calabria: etiopathogenesis and thyroid function.
MedLine Citation:
PMID:  8077616     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
An endemic goiter study was carried out in a vast territory of the Calabria region, including the provinces of Catanzaro and Cosenza. About 50% of 7231 school-children, aged between 6 and 12 years, examined in 34 villages, presented a thyroid enlargement. The high prevalence of goiter seems to be related to a moderate iodine deficiency intake indicated by a mild urinary iodine excretion (lower than 100 micrograms/g creatinine). In a few villages, in which a two year voluntary iodine prophylaxis was carried out, an increase in the urinary iodine excretion with a decreased goiter prevalence was observed. A slight increase in TT3, FT3 and TSH in one endemic area studied, compared to the control area, was also observed. These data suggest that an effective program of iodoprophylaxis is fundamental in this region as well.
Authors:
S Andò; M Maggiolini; A Di Carlo; A Diodato; A Bloise; G P De Luca; V Pezzi; D Sisci; A Mariano; V Macchia
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of endocrinological investigation     Volume:  17     ISSN:  0391-4097     ISO Abbreviation:  J. Endocrinol. Invest.     Publication Date:  1994 May 
Date Detail:
Created Date:  1994-10-05     Completed Date:  1994-10-05     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7806594     Medline TA:  J Endocrinol Invest     Country:  ITALY    
Other Details:
Languages:  eng     Pagination:  329-33     Citation Subset:  IM    
Affiliation:
Dipartimento di Biologia Cellulare, Università della Calabria, Rende, Cosenza, Italy.
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MeSH Terms
Descriptor/Qualifier:
Child
Goiter, Endemic / epidemiology*,  physiopathology
Humans
Iodine / urine
Italy / epidemiology
Prevalence
Thyroid Gland / physiopathology*
Thyroid Hormones / blood*
Thyrotropin / blood
Chemical
Reg. No./Substance:
0/Thyroid Hormones; 7553-56-2/Iodine; 9002-71-5/Thyrotropin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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