Document Detail


End-tidal carbon dioxide monitoring indicates recovery from cardiogenic shock in patients receiving percutaneous cardiopulmonary support.
MedLine Citation:
PMID:  15951983     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The aim of this study was to examine the prognostic value of monitoring end-tidal carbon dioxide (ETCO(2)) levels for patients in cardiogenic shock undergoing percutaneous cardiopulmonary support (PCPS). Fifteen patients in whom PCPS was used to treat cardiogenic shock were enrolled in this study. For hemodynamic measurements, a thermodilution catheter was inserted into the pulmonary artery and an infrared absorption sensor was placed in the main stream of exhaled air between the respiration tube and the respirator to measure ETCO(2) levels. Nine patients (group II, 60%) died of multiple organ failure. In the six survivors (group I), there was a significant increase in average ETCO(2) level from 8.8 +/- 3.9 mmHg before treatment to 20.5 +/- 2.1 mmHg 24 h after the start of PCPS compared with values in group II patients (8.8 +/- 3.9 mmHg, P = 0.0411). Also, serum lactate concentrations fell significantly in group I patients (group I 2.8 +/- 0.47 mmol/l, group II 9.0 +/- 2.31 mmol/l, P = 0.0435). The mean ETCO(2) level in group I patients gradually returned to 23 mmHg, which was within the normal healthy range; these patients were successfully weaned from PCPS. These results suggest that, in cardiogenic shock patients, ETCO(2) level is a possible index of cardiac recovery during PCPS support.
Authors:
Takuji Yoshida; Masazumi Watanabe; Mikiko Murakami; Hitoshi Furukawa; Hideki Nakahara
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of artificial organs : the official journal of the Japanese Society for Artificial Organs     Volume:  8     ISSN:  1434-7229     ISO Abbreviation:  J Artif Organs     Publication Date:  2005  
Date Detail:
Created Date:  2005-06-13     Completed Date:  2005-11-01     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  9815648     Medline TA:  J Artif Organs     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  63-6     Citation Subset:  IM    
Affiliation:
Department of Clinical Engineering Technology, Tokyo Metropolitan Hiroo General Hospital, Tokyo, Japan.
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MeSH Terms
Descriptor/Qualifier:
Carbon Dioxide / analysis*
Cardiac Output
Heart-Lung Machine*
Hemodynamics
Humans
Shock, Cardiogenic / physiopathology*,  therapy*
Tidal Volume
Time Factors
Chemical
Reg. No./Substance:
124-38-9/Carbon Dioxide

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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