| End-tidal CO2 as a function of tidal volume in mechanically ventilated infants. | |
| | |
MedLine Citation:
|
PMID: 14703593 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
OBJECTIVE: To test the hypothesis that end-tidal CO(2) (PETCO(2)) varies with tidal volume (Vt) in preterm infants. DESIGN: Intervention study, nonrandomized trial. SETTING: Neonatal ICU, regional referral center. SUBJECTS: 29 preterm infants 790 to 2135 g in weight requiring mechanical ventilation studied on 73 occasions. INTERVENTION: Measurement of PETCO(2) during variations of Vt. MEASUREMENT: Statistical correlation of PETCO(2) to Vt. Result: PETCO(2) is minimal when Vt is either too low or too high. CONCLUSION: Vt, through its effect on dead space/Vt (Vd/Vt) ratios and arterial-alveolar CO(2) differences, has a significant effect on PETCO(2). Observation of PETCO(2) across a range of Vt can be used to select an appropriate Vt for preterm infants requiring mechanical ventilation. |
| | |
Authors:
|
Karen J Greer; Winslade A Bowen; Alfred N Krauss |
Related Documents
:
|
7449403 - Atelectasis associated with mechanical ventilation for hyaline membrane disease. 22270963 - Septicaemia due to enteric organisms is a later event in surgical infants requiring par... 19142293 - Effect of presumptive co-trimoxazole prophylaxis on pneumococcal colonization rates, se... |
Publication Detail:
|
Type: Clinical Trial; Journal Article |
Journal Detail:
|
Title: American journal of perinatology Volume: 20 ISSN: 0735-1631 ISO Abbreviation: Am J Perinatol Publication Date: 2003 Nov |
Date Detail:
|
Created Date: 2004-01-02 Completed Date: 2004-04-08 Revised Date: 2004-11-17 |
Medline Journal Info:
|
Nlm Unique ID: 8405212 Medline TA: Am J Perinatol Country: United States |
Other Details:
|
Languages: eng Pagination: 447-51 Citation Subset: IM |
Affiliation:
|
Perinatology Center, Department of Pediatrics, New York Presbyterian Hospital-Weill Medical College of Cornell University, New York, New York 10021, USA. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Birth Weight Carbon Dioxide / physiology* Female Gestational Age Humans Infant, Newborn / physiology* Intensive Care, Neonatal / methods Male Pulmonary Gas Exchange / physiology* Respiration, Artificial* Tidal Volume / physiology* |
| Chemical | |
Reg. No./Substance:
|
124-38-9/Carbon Dioxide |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Trends in the NICU: a review of 25 years' experience.
Next Document: Low-birth-weight neonates exhibit a physiological set-point to regulate CO2: an untapped potential t...