| End-stage coxarthrosis and gonarthrosis. Aetiology, clinical patterns and radiological features of idiopathic osteoarthritis. | |
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MedLine Citation:
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PMID: 10888705 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVES: To determine and compare the aetiological background, clinical patterns and radiological features of idiopathic osteoarthritis (OA) of the hip and the knee warranting arthroplasty. METHODS: A total of 402 Caucasians consecutively undergoing total hip replacement (THR) or total knee replacement (TKR) for idiopathic OA at a major centre was surveyed. RESULTS: Previous joint injury was more common in the TKR group (P < 0.0001). However, both groups manifested a mixed occupational background, body mass indices similar to the general population and a predominance of females (F:M = 1.3-1.4:1). The TKR group had a significantly younger age of symptom onset (56 yr) than the THR group (61 yr) but both groups had a tendency to bilateral arthroplasty (33%), nodal involvement (54-59%), a significant excess of right-sided replacements (1.8:1, THR; 2.2:1, TKR) and similar levels of pre-operative pain and disability. Up to 40% of hips manifested acetabular dysplasia and 10% possible previous slipped upper femoral epiphyses. Eighty-five per cent with end-stage coxarthrosis or gonarthrosis had an identical pattern of radiographic disease contralaterally. CONCLUSIONS: Our data suggest the importance of a constitutional tendency to idiopathic, end-stage OA, a disorder traditionally associated with environmental factors leading to 'wear and tear'. |
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Authors:
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J Chitnavis; J S Sinsheimer; M A Suchard; K Clipsham; A J Carr |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Rheumatology (Oxford, England) Volume: 39 ISSN: 1462-0324 ISO Abbreviation: Rheumatology (Oxford) Publication Date: 2000 Jun |
Date Detail:
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Created Date: 2000-09-08 Completed Date: 2000-09-08 Revised Date: 2007-09-06 |
Medline Journal Info:
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Nlm Unique ID: 100883501 Medline TA: Rheumatology (Oxford) Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 612-9 Citation Subset: AIM; IM |
Affiliation:
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Nuffield Orthopaedic Centre, Headington, Oxford OX3 7LD, UK and. University of California, Los Angeles, CA, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Age of Onset Aged Aged, 80 and over Analgesics / therapeutic use Arthroplasty, Replacement, Hip Arthroplasty, Replacement, Knee Body Mass Index Disease Progression Female Humans Male Middle Aged Occupations Osteoarthritis, Hip / etiology, physiopathology*, radiography Osteoarthritis, Knee / etiology, physiopathology*, radiography Pain / drug therapy, etiology Sex Factors Total Quality Management |
| Chemical | |
Reg. No./Substance:
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0/Analgesics |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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