| Encouraging early clinical experience with deliberately delayed temporary fetoscopic tracheal occlusion for the prenatal treatment of life-threatening right and left congenital diaphragmatic hernias. | |
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MedLine Citation:
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PMID: 16601345 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: In order to assess the effect of deliberately delayed percutaneous fetoscopic tracheal occlusion on survival of fetuses with life-threatening congenital diaphragmatic hernia. METHODS: Eight fetuses with life-threatening congenital diaphragmatic hernia underwent fetoscopic tracheal balloon occlusion between 29 + 0 and 32 + 4 weeks of gestation. Delayed occlusion was chosen in order to minimize potentially negative pulmonary effects from premature delivery as a result of fetal surgery. In addition, we wanted to become able to provide all available postnatal intensive care treatment means in these patients. RESULTS: Six of the 8 fetuses survived to discharge from hospital. CONCLUSION: Delayed fetoscopic tracheal balloon occlusion may be rewarded with lung growth sufficient to allow survival of fetuses with life-threatening congenital diaphragmatic hernia. |
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Authors:
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Thomas Kohl; Ulrich Gembruch; Barbara Filsinger; Rudolf Hering; Jorgen Bruhn; Kristina Tchatcheva; Sebastian Aryee; Axel Franz; Axel Heep; Andreas Muller; Peter Bartmann; Stefan Loff; Stuart Hosie; Wolfgang Neff; Thomas Schaible; |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Fetal diagnosis and therapy Volume: 21 ISSN: 1015-3837 ISO Abbreviation: Fetal. Diagn. Ther. Publication Date: 2006 |
Date Detail:
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Created Date: 2006-04-07 Completed Date: 2006-08-10 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 9107463 Medline TA: Fetal Diagn Ther Country: Switzerland |
Other Details:
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Languages: eng Pagination: 314-8 Citation Subset: IM |
Copyright Information:
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Copyright 2006 S. Karger AG, Basel. |
Affiliation:
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German Center for Fetal Surgery and Minimally Invasive Therapy, University Hospital of Bonn, Germany. thomas.kohl@ukb.uni-bonn.de |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Balloon Occlusion* Female Fetal Diseases / surgery* Fetoscopy* Gestational Age Hernia, Diaphragmatic / congenital*, surgery* Humans Pregnancy Time Factors Trachea* Ultrasonography, Prenatal |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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