Document Detail

Encouraging early clinical experience with deliberately delayed temporary fetoscopic tracheal occlusion for the prenatal treatment of life-threatening right and left congenital diaphragmatic hernias.
MedLine Citation:
PMID:  16601345     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: In order to assess the effect of deliberately delayed percutaneous fetoscopic tracheal occlusion on survival of fetuses with life-threatening congenital diaphragmatic hernia. METHODS: Eight fetuses with life-threatening congenital diaphragmatic hernia underwent fetoscopic tracheal balloon occlusion between 29 + 0 and 32 + 4 weeks of gestation. Delayed occlusion was chosen in order to minimize potentially negative pulmonary effects from premature delivery as a result of fetal surgery. In addition, we wanted to become able to provide all available postnatal intensive care treatment means in these patients. RESULTS: Six of the 8 fetuses survived to discharge from hospital. CONCLUSION: Delayed fetoscopic tracheal balloon occlusion may be rewarded with lung growth sufficient to allow survival of fetuses with life-threatening congenital diaphragmatic hernia.
Thomas Kohl; Ulrich Gembruch; Barbara Filsinger; Rudolf Hering; Jorgen Bruhn; Kristina Tchatcheva; Sebastian Aryee; Axel Franz; Axel Heep; Andreas Muller; Peter Bartmann; Stefan Loff; Stuart Hosie; Wolfgang Neff; Thomas Schaible;
Related Documents :
2186545 - Experimental congenital obstructive uropathy.
7879825 - Case report: congenital absence of the left pulmonary artery accompanied by ipsilateral...
9241775 - Different grades of medial hypertrophy and intimal changes in small pulmonary arteries ...
19664575 - Palliative procedures for congenital heart defects.
24861255 - Spontaneous coronary artery dissection.
7192945 - Effects of fentanyl on adrenergic function in canine coronary arteries.
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Fetal diagnosis and therapy     Volume:  21     ISSN:  1015-3837     ISO Abbreviation:  Fetal. Diagn. Ther.     Publication Date:  2006  
Date Detail:
Created Date:  2006-04-07     Completed Date:  2006-08-10     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  9107463     Medline TA:  Fetal Diagn Ther     Country:  Switzerland    
Other Details:
Languages:  eng     Pagination:  314-8     Citation Subset:  IM    
Copyright Information:
Copyright 2006 S. Karger AG, Basel.
German Center for Fetal Surgery and Minimally Invasive Therapy, University Hospital of Bonn, Germany.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Balloon Occlusion*
Fetal Diseases / surgery*
Gestational Age
Hernia, Diaphragmatic / congenital*,  surgery*
Time Factors
Ultrasonography, Prenatal

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Conduction system disease in fetuses evaluated for irregular cardiac rhythm.
Next Document:  The effect of imatinib mesylate on the contractility of isolated rabbit myometrial strips.