Document Detail


Encephalopathy after furosemide use in nephrotic syndrome.
MedLine Citation:
PMID:  17316196     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
An 18-year-old girl with nephrotic syndrome presented with a life-threatening respiratory failure and a severe encephalopathy, shortly after being started on furosemide. The evaluation confirmed furosemide as the sole culprit for the clinical manifestations. This case highlights an unpredictable dose-response relationship of furosemide. The pathophysiological basis, differential diagnosis and clinical implications of the observed findings are discussed.
Authors:
Ajay P Sharma; Joanne Grimmer
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of paediatrics and child health     Volume:  43     ISSN:  1034-4810     ISO Abbreviation:  J Paediatr Child Health     Publication Date:  2007 Mar 
Date Detail:
Created Date:  2007-02-23     Completed Date:  2007-04-16     Revised Date:  2007-09-24    
Medline Journal Info:
Nlm Unique ID:  9005421     Medline TA:  J Paediatr Child Health     Country:  Australia    
Other Details:
Languages:  eng     Pagination:  188-90     Citation Subset:  IM    
Affiliation:
Department of Pediatrics, University of Western Ontario, London, Ontario, Canada. ajay.sharma@lhsc.on.ca
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Brain
Brain Diseases* / diagnosis,  physiopathology
Diagnosis, Differential
Female
Furosemide / administration & dosage,  therapeutic use*
Humans
Nephrotic Syndrome / drug therapy*
Chemical
Reg. No./Substance:
54-31-9/Furosemide

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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