| Encephalopathy and MRI abnormalities in fat embolism syndrome: a case report. | |
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MedLine Citation:
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PMID: 18971877 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: Fat embolization and fat embolism syndrome are poorly understood complications of skeletal trauma. Fat embolism syndrome is a clinical diagnosis, and patients typically present with a classic triad of petechial rash, pulmonary distress, and neurologic dysfunction. The incomplete form of the syndrome (i.e., cerebral fat embolism) is a more challenging clinical diagnosis in which brain magnetic resonance imaging may be a valuable tool. Fat embolism syndrome can be a life-threatening condition, but the latent form that occurs 24 to 72 hours after the trauma is frequently described as a self-limiting condition. CASE REPORT: In this report, we present the case of a 32-year-old man with fat embolism syndrome and a prolonged coma with persistent cerebral dysfunction. Brain magnetic resonance imaging revealed multiple white and grey matter lesions suggestive of vasogenic edema and punctuate hemorrhage, consistent with a diagnosis of cerebral fat emboli. CONCLUSIONS: The pathogenesis and treatment options of fat embolism syndrome are reviewed based on available literature, and the usefulness of brain magnetic resonance imaging is discussed. |
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Authors:
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Christianne J Buskens; Jan Willem C Gratama; Mike Hogervorst; Roeland B van Leeuwen; Johannes H Rommes; Peter E Spronk |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Medical science monitor : international medical journal of experimental and clinical research Volume: 14 ISSN: 1643-3750 ISO Abbreviation: Med. Sci. Monit. Publication Date: 2008 Nov |
Date Detail:
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Created Date: 2008-10-30 Completed Date: 2008-12-12 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9609063 Medline TA: Med Sci Monit Country: Poland |
Other Details:
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Languages: eng Pagination: CS125-9 Citation Subset: IM |
Affiliation:
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Department of Surgery, Gelre Ziekenhuizen, Apeldoorn, The Netherlands. C.Buskens@gelre.nl |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Brain Damage, Chronic / pathology* Embolism, Fat / pathology* Humans Magnetic Resonance Imaging Male Syndrome |
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