Document Detail


Encephalocraniocutaneous lipomatosis and the Proteus syndrome: distinct entities with overlapping manifestations.
MedLine Citation:
PMID:  1621755     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We have studied three children with cutaneous (epidermal nevi), subcutaneous (lipomas, plantar skin thickening), vascular (hemangioma, lymphangioma), skeletal (osteoma, exostosis, localized hypertrophy), and neurological (hydrocephaly, lissencephaly, partial agenesis of the corpus callosum) developmental defects associated with the Proteus syndrome and related hamartoneoplastic conditions. We compared our findings in these three patients with those of 50 others with Proteus syndrome and nine with encephalocraniocutaneous lipomatosis (ECCL) reported in the literature. We found that Proteus syndrome and ECCL have distinct identities even though some clinical manifestations are shared by both and a few patients have manifestations of both conditions.
Authors:
S McCall; M I Ramzy; J K Curé; G S Pai
Related Documents :
16008655 - Blue rubber bleb naevus syndrome associated with cortical blindness.
6310795 - Vascular anomalies in association with osteodystrophies--a spectrum.
1532715 - Globus pallidus calcification in down syndrome with progressive neurologic deficits.
16012215 - Total oral rehabilitation in a patient with portwine stains.
3147155 - Severe aortic stenosis in systemic lupus erythematosus and mucopolysaccharidosis type i...
3425595 - The cfc syndrome--report of the first two cases outside the united states.
Publication Detail:
Type:  Case Reports; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.    
Journal Detail:
Title:  American journal of medical genetics     Volume:  43     ISSN:  0148-7299     ISO Abbreviation:  Am. J. Med. Genet.     Publication Date:  1992 Jul 
Date Detail:
Created Date:  1992-08-03     Completed Date:  1992-08-03     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7708900     Medline TA:  Am J Med Genet     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  662-8     Citation Subset:  IM    
Affiliation:
Department of Pediatrics, Medical University of South Carolina, Charleston 29425.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Bone Neoplasms / classification,  complications,  diagnosis*
Child
Child, Preschool
Diagnosis, Differential
Female
Humans
Infant, Newborn
Lipomatosis / classification,  complications,  diagnosis*
Male
Proteus Syndrome / chemically induced,  classification,  diagnosis*
Skin Neoplasms / classification,  complications,  diagnosis*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Hypothesis: Jadassohn nevus phakomatosis: a paracrinopathy with variable phenotype.
Next Document:  Variability versus heterogeneity in syndromal hypothalamic hamartoblastoma and related disorders: re...