Document Detail


Encapsulation of folic acid and its stability in sodium alginate-pectin-poly(ethylene oxide) electrospun fibres.
MedLine Citation:
PMID:  22703229     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
In this study, we investigated the effect of alginate-pectin-poly(ethylene oxide) (PEO) electrospun fibres on the stability of folic acid. Fibre-forming solutions containing folic acid were prepared by blending low- or medium-viscosity alginate with pectin. PEO was added to make the electrospinning process possible. Folic acid encapsulated in electrospun fibres achieved close to 100% retention when stored in the dark at pH 3 after 41 days of storage. By contrast, recovery of unencapsulated folic acid was 0% and 8% within the first day when stored at pH 3 in the presence and the absence of light, respectively. Electrospun fibres produced from the combination of alginate-pectin resulted in higher retention of folic acid compared to that of alginate alone. Nucleic magnetic resonance and FTIR results show that folic acid has been encapsulated in electrospun fibres through physical entrapment.
Authors:
Solmaz Alborzi; Loong-Tak Lim; Yukio Kakuda
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-6-18
Journal Detail:
Title:  Journal of microencapsulation     Volume:  -     ISSN:  1464-5246     ISO Abbreviation:  -     Publication Date:  2012 Jun 
Date Detail:
Created Date:  2012-6-18     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8500513     Medline TA:  J Microencapsul     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
Department of Food Science, University of Guelph , Guelph, ON , Canada.
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