Document Detail

Enantioselective trapping of phosphoramidate ammonium ylides with imino esters for synthesis of 2,3-diaminosuccinic acid derivatives.
MedLine Citation:
PMID:  23358554     Owner:  NLM     Status:  Publisher    
A highly enantioselective trapping of protic phosphoramidate ammonium ylides with α-imino esters is reported. The intriguing Rh(2)(OAc)(4) and chiral Brønsted acid co-catalyzed three-component Mannich-type reaction of a diazo compound, a phosphoramidate, and an α-imino ester provides a rapid and efficient access to 2,3-diaminosuccinic acid derivatives with a high level control of diastereo- and enantioselectivity.
Jun Jiang; Xiaochu Ma; Shunying Liu; Yu Qian; Fengping Lv; Lin Qiu; Xiang Wu; Wenhao Hu
Related Documents :
8568814 - Dibenzoxepinone hydroxylamines and hydroxamic acids: dual inhibitors of cyclooxygenase ...
22182964 - Cvd graphene vs. highly ordered pyrolytic graphite for use in electroanalytical sensing.
22162274 - Analysis of nad 2d-nmr spectra of saturated fatty acids in polypeptide aligning media b...
22120064 - Peculiar patterns of amino acid substitution and conservation in the fast evolving tuni...
604424 - A new method for determination of inorganic phosphorus in serum without deproteinization.
24667634 - Increase of epa-derived hydroxy, epoxy and dihydroxy fatty acid levels in human plasma ...
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2013-1-29
Journal Detail:
Title:  Chemical communications (Cambridge, England)     Volume:  -     ISSN:  1364-548X     ISO Abbreviation:  Chem. Commun. (Camb.)     Publication Date:  2013 Jan 
Date Detail:
Created Date:  2013-1-29     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9610838     Medline TA:  Chem Commun (Camb)     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Shanghai Engineering Research Center of Molecular Therapeutics and New Drug Development, East China Normal University, 3663 North Zhongshan Rd., Shanghai, 200062, China.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Tanshinone IIA inhibits the growth of pancreatic cancer BxPC?3 cells by decreasing protein expressio...
Next Document:  Quantification of blood flow in internal cerebral artery by optical flow method on digital subtracti...