Document Detail


Enantioselective trapping of phosphoramidate ammonium ylides with imino esters for synthesis of 2,3-diaminosuccinic acid derivatives.
MedLine Citation:
PMID:  23358554     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
A highly enantioselective trapping of protic phosphoramidate ammonium ylides with α-imino esters is reported. The intriguing Rh(2)(OAc)(4) and chiral Brønsted acid co-catalyzed three-component Mannich-type reaction of a diazo compound, a phosphoramidate, and an α-imino ester provides a rapid and efficient access to 2,3-diaminosuccinic acid derivatives with a high level control of diastereo- and enantioselectivity.
Authors:
Jun Jiang; Xiaochu Ma; Shunying Liu; Yu Qian; Fengping Lv; Lin Qiu; Xiang Wu; Wenhao Hu
Related Documents :
23963294 - The dual role of zn-acid medium for one-step rapid synthesis of m@rgo (m = au, pt, pd a...
10386944 - N-substituted 4-(5-indolyl)benzoic acids. synthesis and evaluation of steroid 5alpha-re...
14611854 - Linearized and truncated microcystin analogues as inhibitors of protein phosphatases 1 ...
9443624 - Antiangiogenic and antiproliferative activity of suramin analogues.
7919904 - Immune modulation by polyunsaturated fatty acids during nutritional therapy: interactio...
16525544 - Supramolecular assemblies of crown-containing 2-styrylbenzothiazole with amino acids.
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2013-1-29
Journal Detail:
Title:  Chemical communications (Cambridge, England)     Volume:  -     ISSN:  1364-548X     ISO Abbreviation:  Chem. Commun. (Camb.)     Publication Date:  2013 Jan 
Date Detail:
Created Date:  2013-1-29     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9610838     Medline TA:  Chem Commun (Camb)     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
Shanghai Engineering Research Center of Molecular Therapeutics and New Drug Development, East China Normal University, 3663 North Zhongshan Rd., Shanghai, 200062, China. whu@chem.ecnu.edu.cn.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Tanshinone IIA inhibits the growth of pancreatic cancer BxPC?3 cells by decreasing protein expressio...
Next Document:  Quantification of blood flow in internal cerebral artery by optical flow method on digital subtracti...