| Enantioselective synthesis of aspergillide B. | |
| | |
MedLine Citation:
|
PMID: 19661704 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
The enantioselective synthesis of aspergillide B, a 14-membered macrocyclic cytotoxin, was achieved in a 49% yield via 7 steps from a synthetic intermediate of aspergillide C. The spectroscopic data and specific rotation value for the synthetic material matched those of natural aspergillide B. |
| | |
Authors:
|
Tomohiro Nagasawa; Shigefumi Kuwahara |
Related Documents
:
|
17137384 - Chiral diols: a new class of additives for direct aldol reaction catalyzed by l-proline. 20523004 - Chiral induction by cinchona alkaloids in the rhodium(ii) catalyzed o-h insertion react... 20939594 - A strategy to synthesize taxol side chain and (-)-epi cytoxazone via chiral brønsted a... 20623064 - Highly efficient asymmetric organocatalytic friedel-crafts alkylation of indoles with a... 2990494 - A novel biologically active seleno-organic compound--v. inhibition by ebselen (pz 51) o... 15260124 - Anti-narcoleptic agent modafinil and its sulfone: a novel facile synthesis and potentia... |
Publication Detail:
|
Type: Journal Article; Research Support, Non-U.S. Gov't Date: 2009-08-07 |
Journal Detail:
|
Title: Bioscience, biotechnology, and biochemistry Volume: 73 ISSN: 1347-6947 ISO Abbreviation: Biosci. Biotechnol. Biochem. Publication Date: 2009 Aug |
Date Detail:
|
Created Date: 2009-08-24 Completed Date: 2009-11-30 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 9205717 Medline TA: Biosci Biotechnol Biochem Country: Japan |
Other Details:
|
Languages: eng Pagination: 1893-4 Citation Subset: IM |
Affiliation:
|
Laboratory of Applied Bioorganic Chemistry, Graduate School of Agricultural Science, Tohoku University, Sendai, Japan. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Cytotoxins
/
chemical synthesis,
chemistry Macrolides / chemical synthesis*, chemistry* Stereoisomerism Substrate Specificity |
| Chemical | |
Reg. No./Substance:
|
0/Cytotoxins; 0/Macrolides; 0/aspergillide B |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Comparison of proteolytic-related gene expression in the skeletal muscles of layer and broiler chick...
Next Document: Potato tuber cell expansion-inducing activity of stereochemically restricted JA analogs.