Document Detail

Enantioselective synthesis of aspergillide B.
MedLine Citation:
PMID:  19661704     Owner:  NLM     Status:  MEDLINE    
The enantioselective synthesis of aspergillide B, a 14-membered macrocyclic cytotoxin, was achieved in a 49% yield via 7 steps from a synthetic intermediate of aspergillide C. The spectroscopic data and specific rotation value for the synthetic material matched those of natural aspergillide B.
Tomohiro Nagasawa; Shigefumi Kuwahara
Related Documents :
17137384 - Chiral diols: a new class of additives for direct aldol reaction catalyzed by l-proline.
20523004 - Chiral induction by cinchona alkaloids in the rhodium(ii) catalyzed o-h insertion react...
20939594 - A strategy to synthesize taxol side chain and (-)-epi cytoxazone via chiral brønsted a...
20623064 - Highly efficient asymmetric organocatalytic friedel-crafts alkylation of indoles with a...
2990494 - A novel biologically active seleno-organic compound--v. inhibition by ebselen (pz 51) o...
15260124 - Anti-narcoleptic agent modafinil and its sulfone: a novel facile synthesis and potentia...
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2009-08-07
Journal Detail:
Title:  Bioscience, biotechnology, and biochemistry     Volume:  73     ISSN:  1347-6947     ISO Abbreviation:  Biosci. Biotechnol. Biochem.     Publication Date:  2009 Aug 
Date Detail:
Created Date:  2009-08-24     Completed Date:  2009-11-30     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9205717     Medline TA:  Biosci Biotechnol Biochem     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  1893-4     Citation Subset:  IM    
Laboratory of Applied Bioorganic Chemistry, Graduate School of Agricultural Science, Tohoku University, Sendai, Japan.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Cytotoxins / chemical synthesis,  chemistry
Macrolides / chemical synthesis*,  chemistry*
Substrate Specificity
Reg. No./Substance:
0/Cytotoxins; 0/Macrolides; 0/aspergillide B

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Comparison of proteolytic-related gene expression in the skeletal muscles of layer and broiler chick...
Next Document:  Potato tuber cell expansion-inducing activity of stereochemically restricted JA analogs.