Document Detail

Enantioselective cyclization of enamide-ynes and application to the synthesis of the kopsifoline core.
MedLine Citation:
PMID:  23772095     Owner:  NLM     Status:  Publisher    
We report the palladium-catalyzed enantioselective cyclization of 1,6-enamidynes to form spirocyclic ring systems. We applied this methodology to the concise synthesis of the skeletal core of the kopsifoline alkaloids.
Britton K Corkey; Stephen T Heller; Yi-Ming Wang; F Dean Toste
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Publication Detail:
Journal Detail:
Title:  Tetrahedron     Volume:  69     ISSN:  0040-4020     ISO Abbreviation:  Tetrahedron     Publication Date:  2013 Jul 
Date Detail:
Created Date:  2013-6-17     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  2984170R     Medline TA:  Tetrahedron     Country:  -    
Other Details:
Languages:  ENG     Pagination:  5640-5646     Citation Subset:  -    
Department of Chemistry, University of California, Berkeley, Berkeley, CA 94720, USA.
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