| Enantioselective Construction of Pyrroloindolines via Chiral Phosphoric Acid Catalyzed Cascade Michael Addition-Cyclization of Tryptamines. | |
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MedLine Citation:
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PMID: 22928846 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Enantioselective construction of pyrroloindolines via chiral phosphoric acid catalyzed cascade Michael addition-cyclization of tryptamines has been realized. With 5 mol % of chiral phosphoric acid, enantioenriched pyrroloindoline derivatives were obtained in good yields and enantioselectivity (up to 95% yield and 83% ee) from readily available tryptamines and enones. |
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Authors:
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Quan Cai; Chuan Liu; Xiao-Wei Liang; Shu-Li You |
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Publication Detail:
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Type: Journal Article Date: 2012-08-28 |
Journal Detail:
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Title: Organic letters Volume: 14 ISSN: 1523-7052 ISO Abbreviation: Org. Lett. Publication Date: 2012 Sep |
Date Detail:
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Created Date: 2012-09-07 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 100890393 Medline TA: Org Lett Country: United States |
Other Details:
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Languages: eng Pagination: 4588-90 Citation Subset: IM |
Affiliation:
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State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences , 345 Lingling Lu, Shanghai 200032, China. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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