| Enalapril following captopril-induced nephrotic syndrome. | |
| | |
MedLine Citation:
|
PMID: 3008324 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
The development of proteinuria, and more rarely nephrotic syndrome, has been seen with the use of the first orally active converting-enzyme inhibitor captopril. Both of these side effects appear to occur more frequently when the drug is used at higher dose, particularly in the presence of renal impairment. We have used enalapril, a new orally active converting-enzyme inhibitor in the treatment of a patient with drug-resistant hypertension and renal impairment who previously developed nephrotic syndrome with captopril. Recurrence of the nephrotic syndrome was not seen in this patient during a period of 20 months on enalapril. On the contrary, urinary protein excretion over the same period was reduced to around 1 g in 24 hours. Our experience would suggest that enalapril may usefully be substituted for captopril in the treatment of hypertensive patients in whom the latter has caused proteinuria or nephrotic syndrome. |
| | |
Authors:
|
D J Webb; A B Atkinson |
Related Documents
:
|
1251764 - The effect of indomethacin on proteinuria and kidney function in the nephrotic syndrome. 1962674 - Acute venous thrombosis of spleno-mesenteric portal axis: an unusual localization of th... 3983894 - Detection of antithrombin iii microheterogeneity. 21511514 - Delayed dislocation of an injectable hydrophilic acrylic lens after nd:yag capsulotomy ... 3792604 - Kasabach-merritt syndrome with disseminated intravascular coagulopathy treated by excha... 19864154 - The management of thoracic inlet syndrome associated with hurler's syndrome: a novel su... |
Publication Detail:
|
Type: Case Reports; Journal Article |
Journal Detail:
|
Title: Scottish medical journal Volume: 31 ISSN: 0036-9330 ISO Abbreviation: Scott Med J Publication Date: 1986 Jan |
Date Detail:
|
Created Date: 1986-05-13 Completed Date: 1986-05-13 Revised Date: 2004-11-17 |
Medline Journal Info:
|
Nlm Unique ID: 2983335R Medline TA: Scott Med J Country: SCOTLAND |
Other Details:
|
Languages: eng Pagination: 30-2 Citation Subset: IM |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adult Captopril / adverse effects*, therapeutic use Enalapril / therapeutic use* Female Humans Hypertension / drug therapy Nephrotic Syndrome / chemically induced*, urine Proteinuria |
| Chemical | |
Reg. No./Substance:
|
62571-86-2/Captopril; 75847-73-3/Enalapril |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Transfusion-associated LAV/HTLV-III infections in Switzerland. Report of 2 cases
Next Document: Occurrence of peptide and clavine ergot alkaloids in tall fescue grass.