Document Detail


Emulsion Reactors: A New Technique for the Preparation of Molecular Imaging Probes.
MedLine Citation:
PMID:  22532271     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Emulsions for labeling: A new strategy for the preparation of radiolabeled compounds with the use emulsions was developed. This biocompatible platform demonstrated enhanced yields for labeling biovectors with (99m) Tc, (18) F, and (68) Ga. Enhancements included reduction in the amount of starting material required, a decrease in the number of radiochemical impurities, and the ability to perform reactions at room temperature.
Authors:
Ryan W Simms; Dong Hyun Kim; Darren M Weaver; Chitra Sundararajan; Megan Blacker; Karin A Stephenson; John F Valliant
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-4-25
Journal Detail:
Title:  Chemistry (Weinheim an der Bergstrasse, Germany)     Volume:  -     ISSN:  1521-3765     ISO Abbreviation:  -     Publication Date:  2012 Apr 
Date Detail:
Created Date:  2012-4-25     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9513783     Medline TA:  Chemistry     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
Affiliation:
Centre for Probe Development and Commercialization, Burke Science Building, Room B231, McMaster University, 1280 Main Street West, Hamilton, Ontario L8S 4K1 (Canada), Fax: (+1) 905-522-2509.
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