Document Detail


Empirical validation of the Essen-Möller probability of paternity.
MedLine Citation:
PMID:  3752079     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The validity of the Essen-Möller formulation probability of paternity is supported by demonstrating its correctness in a model genetic system--the ABO system. An analysis was made of 1,393 paternity cases typed uniformly for HLA-A and -B, ABO, Rh, and MNSs, in which the mother named one man only as the child's father and in which both mother and putative father identified themselves as Caucasian. For purposes of analysis, putative fathers not excluded from paternity by the four systems tested were regarded as actual fathers. The joint distribution of observed triplets of ABO phenotypes is shown to be statistically consistent with expected values, and the fractions of "true" fathers for a given triplet closely approximated the probability of paternity calculated using a realistic prior probability. Recent allegations of fallaciousness of the method by Li and Chakravarty and Aickin are discussed in terms of the results presented.
Authors:
M R Mickey; D W Gjertson; P I Terasaki
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  American journal of human genetics     Volume:  39     ISSN:  0002-9297     ISO Abbreviation:  Am. J. Hum. Genet.     Publication Date:  1986 Jul 
Date Detail:
Created Date:  1986-10-03     Completed Date:  1986-10-03     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  0370475     Medline TA:  Am J Hum Genet     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  123-32     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
ABO Blood-Group System / genetics
Female
Humans
Male
Models, Genetic
Paternity*
Phenotype
Probability*
Chemical
Reg. No./Substance:
0/ABO Blood-Group System
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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