Document Detail


Emotional triggers in myocardial infarction: do they matter?
MedLine Citation:
PMID:  23178642     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Considerable excitement and interest have arisen recently concerning the role that acute emotional triggers may play in precipitating a myocardial infarction (MI). Observational studies have found repeatedly that patients report excessive anger, anxiety, sadness, grief, or acute stress immediately prior to onset of MI, and recent meta-analyses summarizing these findings reported strong associations between MI occurrence and many of these acute emotions. However, it is unclear whether and through what mechanisms acute emotional triggers might influence MI, and whether there is any clinical utility in knowing if or how emotions trigger MI. We debate whether emotional triggers matter by reviewing the recent evidence for the association between acute emotional triggers and MI and by describing the potential pathophysiological characteristics and mechanisms underlying this association and the preventive strategies that could be used to mitigate the risk of acute MI. We also examine whether the study of emotional triggers could influence clinical risk management or changes in clinical practice/management. We offer suggestions for research that might shed light on whether emotional triggers could initiate a paradigm shift in preventive cardiology, or whether acute emotional triggers are either intractable catalysts for, or merely an epiphenomenon of, some MIs.
Authors:
Donald Edmondson; Jonathan D Newman; William Whang; Karina W Davidson
Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural; Review     Date:  2012-11-23
Journal Detail:
Title:  European heart journal     Volume:  34     ISSN:  1522-9645     ISO Abbreviation:  Eur. Heart J.     Publication Date:  2013 Jan 
Date Detail:
Created Date:  2013-01-22     Completed Date:  2013-07-03     Revised Date:  2014-01-23    
Medline Journal Info:
Nlm Unique ID:  8006263     Medline TA:  Eur Heart J     Country:  England    
Other Details:
Languages:  eng     Pagination:  300-6     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Animals
Anxiety Disorders / complications
Conflict (Psychology)
Depressive Disorder / complications
Disease Models, Animal
Emotions*
Humans
Interpersonal Relations
Myocardial Infarction / psychology*
Risk Factors
Grant Support
ID/Acronym/Agency:
5T32HL007854-16/HL/NHLBI NIH HHS; HL-088117/HL/NHLBI NIH HHS; HL-101663/HL/NHLBI NIH HHS; HL-47540/HL/NHLBI NIH HHS; HL-84034/HL/NHLBI NIH HHS; K24 HL084034/HL/NHLBI NIH HHS; KM1 CA-156709/CA/NCI NIH HHS; P01 HL047540/HL/NHLBI NIH HHS; P01 HL088117/HL/NHLBI NIH HHS; R01 HL115941/HL/NHLBI NIH HHS; RC2 HL101663/HL/NHLBI NIH HHS; UL1 RR024156/RR/NCRR NIH HHS
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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