Document Detail

Emotional stress and reversible myocardial dysfunction.
MedLine Citation:
PMID:  17347529     Owner:  NLM     Status:  MEDLINE    
A growing body of clinical and experimental literature supports a strong association between emotional stress and adverse outcomes from CVD. Effects of emotional stress on coronary blood flow and cardiac arrhythmias provide only a partial explanation. A direct impact of emotional stress on myocardial function has recently received attention as a result of reports of patients presenting with new onset of unexplained reversible heart failure following episodes of emotional stress. Potential mechanisms responsible for myocardial dysfunction following emotional stress remain to be elucidated. This review will explore potential pathophysiologic mechanisms linking emotional stress to adverse cardiovascular outcomes beginning with primary and secondary risk factors and leading to direct effects of emotional stress on reversible myocardial dysfunction.
Deepak Khanna; Hong Kan; Conard Failinger; Abnash C Jain; Mitchell S Finkel
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Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.; Review    
Journal Detail:
Title:  Cardiovascular toxicology     Volume:  6     ISSN:  1530-7905     ISO Abbreviation:  Cardiovasc. Toxicol.     Publication Date:  2006  
Date Detail:
Created Date:  2007-03-09     Completed Date:  2007-04-06     Revised Date:  2007-12-03    
Medline Journal Info:
Nlm Unique ID:  101135818     Medline TA:  Cardiovasc Toxicol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  183-98     Citation Subset:  IM    
Department of Medicine, West Virginia University School of Medicine, Robert C. Byrd Health Sciences Center, Morgantown, WV 26506-9157, USA.
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MeSH Terms
Cardiovascular Diseases / physiopathology,  psychology
Heart / physiopathology*
Models, Cardiovascular
Models, Psychological
Recovery of Function
Stress, Psychological / complications,  physiopathology*
Grant Support

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