Document Detail


Emollients and photo(chemo)therapy: a call for caution.
MedLine Citation:
PMID:  8726639     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: Emollients used for skin care, treatment of a disease or lubrication, before irradiation during the course of phototherapy or photochemotherapy, may significantly interfere with the transmission of UV light and may influence the outcome of the therapy. OBJECTIVE: These experiments should characterize and quantify the possible interactions of usual emollients with UV light transmission. METHOD: The method was an in vitro technique similar to the one already used for the determination of sun protection factors of topical sunscreen preparations. RESULTS: Among the products tested, two showed a significant photoprotection capable of interfering with the course of therapy. Oils enhanced UV light transmission significantly. CONCLUSIONS: Emollients may show significant interference with UV light transmission during phototherapy or photochemotherapy. The outcome and course of the therapy could thus be significantly modified.
Authors:
B Gabard; P Treffel; E Bieli; S Schwab
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Publication Detail:
Type:  In Vitro; Journal Article    
Journal Detail:
Title:  Dermatology (Basel, Switzerland)     Volume:  192     ISSN:  1018-8665     ISO Abbreviation:  Dermatology (Basel)     Publication Date:  1996  
Date Detail:
Created Date:  1996-11-18     Completed Date:  1996-11-18     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  9203244     Medline TA:  Dermatology     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  242-5     Citation Subset:  IM    
Affiliation:
Department of Biopharmacy, Spirig Ltd., Egerkingen, Switzerland.
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MeSH Terms
Descriptor/Qualifier:
Emollients / contraindications,  pharmacology*,  therapeutic use
Models, Theoretical
Photochemotherapy*
Phototherapy*
Ultraviolet Rays
Chemical
Reg. No./Substance:
0/Emollients

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