Document Detail

Emission tomography with 99mTc-pyrophosphate in the diagnosis of acute myocardial infarction.
MedLine Citation:
PMID:  2992989     Owner:  NLM     Status:  MEDLINE    
Electrocardiograms (ECG) and enzyme criteria are usually used to confirm the diagnosis of acute myocardial infarction in the case of chest pain. However, ECG is not always diagnostic. Elevated enzyme values may be due to causes other than myocardial infarction. In uncertain cases, the ECG and enzyme criteria can be supplemented by emission tomography, performed with technetium pyrophosphate that will accumulate in the site of infarction. Twenty-nine patients with suspected acute myocardial infarction were studied with emission tomography. Of these 12 had acute transmural infarction. Both enzyme tests and ECG were diagnostic in only 7 of these 12 cases, 4 had positive enzyme tests but a nondiagnostic ECG and in one case neither enzymes nor ECG were diagnostic. In 11 patients the infarcted myocardial area was detected with emission tomography. Six patients had acute nontransmural infarction. Only 2 of these had positive emission tomography. The chest pain was not due to infarction in 11 patients. All these patients had negative emission tomography. The sensitivity of emission tomography was 92% and specificity 100% in transmural acute infarction. In nontransmural infarction the specificity was only 33%. Emission tomography is a valuable diagnostic tool. It may be the decisive method when ECG and enzymes are not diagnostic. Emission tomography also shows the localization and size of the infarcted area in the myocardium.
L Pöyhönen; A Uusitalo; A Virjo
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  European journal of nuclear medicine     Volume:  10     ISSN:  0340-6997     ISO Abbreviation:  Eur J Nucl Med     Publication Date:  1985  
Date Detail:
Created Date:  1985-10-07     Completed Date:  1985-10-07     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  7606882     Medline TA:  Eur J Nucl Med     Country:  GERMANY, WEST    
Other Details:
Languages:  eng     Pagination:  489-93     Citation Subset:  IM    
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MeSH Terms
Clinical Enzyme Tests
Diphosphates / diagnostic use
Middle Aged
Myocardial Infarction / diagnosis,  radionuclide imaging*
Technetium / diagnostic use
Technetium Tc 99m Pyrophosphate
Tomography, Emission-Computed*
Reg. No./Substance:
0/Diphosphates; 0/Technetium Tc 99m Pyrophosphate; 7440-26-8/Technetium

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