Document Detail


Emerging treatments in myopathies.
MedLine Citation:
PMID:  9363835     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Outstanding improvement has been made in the molecular understanding of several muscle diseases with the application of molecular biological techniques to the investigation of human disorders. The identification of genetic mutations has improved considerably the diagnostic approach to muscular dystrophies, mitochondrial myopathies and ion channel disorders. Important results have been achieved in the field of inflammatory myopathies. With a few exceptions, therapies available are nonspecific and rarely represent a cure for the disease. Molecular medicine offers an opportunity to design new therapeutic strategies based on the pathogenic mechanisms underlying each disease.
Authors:
C Antozzi; P Confalonieri; R Mantegazza; S Di Donato
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  European neurology     Volume:  38     ISSN:  0014-3022     ISO Abbreviation:  Eur. Neurol.     Publication Date:  1997  
Date Detail:
Created Date:  1998-01-29     Completed Date:  1998-01-29     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0150760     Medline TA:  Eur Neurol     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  222-9     Citation Subset:  IM    
Affiliation:
Neuromuscular Research Department, National Neurological Institute C. Besta, Milan, Italy.
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MeSH Terms
Descriptor/Qualifier:
Animals
Deficiency Diseases / complications,  drug therapy
Disease Models, Animal
Gene Therapy / trends
Humans
Immunosuppressive Agents / therapeutic use
Lipid Metabolism, Inborn Errors / complications,  drug therapy
Mitochondrial Myopathies / drug therapy
Muscular Diseases / etiology,  physiopathology,  therapy*
Muscular Dystrophies / physiopathology,  therapy
Myositis / immunology,  physiopathology,  therapy
Tissue Transplantation / trends
Vitamins / therapeutic use
Chemical
Reg. No./Substance:
0/Immunosuppressive Agents; 0/Vitamins

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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