| Emerging treatments in myopathies. | |
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MedLine Citation:
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PMID: 9363835 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Outstanding improvement has been made in the molecular understanding of several muscle diseases with the application of molecular biological techniques to the investigation of human disorders. The identification of genetic mutations has improved considerably the diagnostic approach to muscular dystrophies, mitochondrial myopathies and ion channel disorders. Important results have been achieved in the field of inflammatory myopathies. With a few exceptions, therapies available are nonspecific and rarely represent a cure for the disease. Molecular medicine offers an opportunity to design new therapeutic strategies based on the pathogenic mechanisms underlying each disease. |
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Authors:
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C Antozzi; P Confalonieri; R Mantegazza; S Di Donato |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: European neurology Volume: 38 ISSN: 0014-3022 ISO Abbreviation: Eur. Neurol. Publication Date: 1997 |
Date Detail:
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Created Date: 1998-01-29 Completed Date: 1998-01-29 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0150760 Medline TA: Eur Neurol Country: SWITZERLAND |
Other Details:
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Languages: eng Pagination: 222-9 Citation Subset: IM |
Affiliation:
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Neuromuscular Research Department, National Neurological Institute C. Besta, Milan, Italy. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Deficiency Diseases / complications, drug therapy Disease Models, Animal Gene Therapy / trends Humans Immunosuppressive Agents / therapeutic use Lipid Metabolism, Inborn Errors / complications, drug therapy Mitochondrial Myopathies / drug therapy Muscular Diseases / etiology, physiopathology, therapy* Muscular Dystrophies / physiopathology, therapy Myositis / immunology, physiopathology, therapy Tissue Transplantation / trends Vitamins / therapeutic use |
| Chemical | |
Reg. No./Substance:
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0/Immunosuppressive Agents; 0/Vitamins |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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