| Emerging role of microRNAs in liver diseases. | |
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MedLine Citation:
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PMID: 19960558 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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MicroRNAs are a class of small non-coding RNAs that are found in plants, animals, and some viruses. They modulate the gene function at the post-transcriptional level and act as a fine tuner of various processes, such as development, proliferation, cell signaling, and apoptosis. They are associated with different types and stages of cancer. Recent studies have shown the involvement of microRNAs in liver diseases caused by various factors, such as Hepatitis C, Hepatitis B, metabolic disorders, and by drug abuse. This review highlights the role of microRNAs in liver diseases and their potential use as therapeutic molecules. |
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Authors:
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Shashi Bala; Miguel Marcos; Gyongyi Szabo |
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Publication Detail:
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Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review |
Journal Detail:
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Title: World journal of gastroenterology : WJG Volume: 15 ISSN: 1007-9327 ISO Abbreviation: World J. Gastroenterol. Publication Date: 2009 Dec |
Date Detail:
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Created Date: 2009-12-04 Completed Date: 2010-02-16 Revised Date: 2010-09-28 |
Medline Journal Info:
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Nlm Unique ID: 100883448 Medline TA: World J Gastroenterol Country: China |
Other Details:
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Languages: eng Pagination: 5633-40 Citation Subset: IM |
Affiliation:
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Department of Medicine, University of Massachusetts Medical School, LRB 215, Worcester, MA 01605, USA. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Biological Markers Diagnosis, Differential Fibrosis / pathology Hepacivirus / genetics, metabolism Hepatitis / genetics, virology Humans Immune System / physiology Liver Diseases / genetics*, metabolism, pathology, therapy MicroRNAs / genetics, metabolism* |
| Grant Support | |
ID/Acronym/Agency:
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AA011576-10A1/AA/NIAAA NIH HHS |
| Chemical | |
Reg. No./Substance:
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0/Biological Markers; 0/MicroRNAs |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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