| Emerging management concepts for eosinophilic esophagitis in children. | |
| | |
MedLine Citation:
|
PMID: 21545525 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
|
Eosinophilic esophagitis (EoE) is a newly recognized condition which appears to be increasing in incidence for as yet unknown reasons. It can occur at any age and presents both to gastroenterologists and allergists. Clinical manifestations range from gastrointestinal symptoms (vomiting, feeding difficulties, dysphagia or food bolus impaction) to co-existing atopic conditions (asthma, allergic rhinitis or eczema). The diagnosis requires demonstration of at least 15 eosinophils per high power field on esophageal histology, usually in the context of resistance to proton pump inhibitor treatment or a normal 24-hour esophageal pH monitoring study. The differential diagnosis between EoE and gastroesophageal reflux disease (GERD) can be problematic as there is significant clinical overlap between both conditions. Although difficult-to-manage esophageal strictures are well recognized in patients with long-standing EoE, little is known about risk factors for the development of this complication. There is a paucity of data on both the natural history and optimal long-term management of EoE. Current treatment options include food allergen elimination diets, use of topical aerosolized corticosteroids, or a combination of the two. Pediatric case studies have been provided to illustrate the complexity of decision points which often arise in the management of these patients. This paper aims to discuss the various strategies currently available to clinicians in the management of EoE and highlights gaps in the current evidence base that urgently require further research. |
| | |
Authors:
|
Ralf G Heine; Mark Nethercote; Jeremy Rosenbaum; Katrina J Allen |
Related Documents
:
|
22245295 - Factors influencing urologist treatment preference in surgical management of stone dise... 21180605 - Diagnosis and management of barrett's esophagus for the endoscopist. 16393045 - Does retrieval fluency contribute to the underconfidence-with-practice effect? 19038655 - Paradigm changes in the role of nutrition for the management of canine and feline uroli... 10174795 - Making strategy: learning by doing. 12285265 - German-polish migration: the elusive search for a german nation-state. |
Publication Detail:
|
Type: JOURNAL ARTICLE Date: 2011-5-4 |
Journal Detail:
|
Title: Journal of gastroenterology and hepatology Volume: - ISSN: 1440-1746 ISO Abbreviation: - Publication Date: 2011 May |
Date Detail:
|
Created Date: 2011-5-6 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 8607909 Medline TA: J Gastroenterol Hepatol Country: - |
Other Details:
|
Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
|
© 2011 Journal of Gastroenterology and Hepatology Foundation and Blackwell Publishing Asia Pty Ltd. |
Affiliation:
|
Department of Gastroenterology & Clinical Nutrition and Royal Children's Hospital, Melbourne, Australia Department of Allergy & Immunology Royal Children's Hospital, Melbourne, Australia Murdoch Childrens Research Institute, Melbourne, Australia Department of Paediatrics, The University of Melbourne, Melbourne, Australia. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Pathogenesis of Alcohol-induced Liver Disease - classical concepts and recent advances.
Next Document: Transseptal Left Heart Catheterization and the Incidence of Persistent Iatrogenic Atrial Septal Defe...