| Emerging role of ISG15 in antiviral immunity. | |
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MedLine Citation:
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PMID: 20946978 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Cells express a plethora of interferon-stimulated genes (ISGs) in response to viral infection. Among these is ISG15, a ubiquitin-like protein (UBL) that can be covalently attached to both host and viral proteins. Here we review recent advances toward understanding the role and mechanism of ISG15 modification in antiviral defense. |
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Authors:
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Brian Skaug; Zhijian J Chen |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't; Review |
Journal Detail:
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Title: Cell Volume: 143 ISSN: 1097-4172 ISO Abbreviation: Cell Publication Date: 2010 Oct |
Date Detail:
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Created Date: 2010-10-15 Completed Date: 2010-11-08 Revised Date: 2011-12-07 |
Medline Journal Info:
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Nlm Unique ID: 0413066 Medline TA: Cell Country: United States |
Other Details:
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Languages: eng Pagination: 187-90 Citation Subset: IM |
Copyright Information:
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Copyright © 2010 Elsevier Inc. All rights reserved. |
Affiliation:
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Department of Molecular Biology, University of Texas Southwestern Medical Center, Dallas, TX 75390-9148, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Cytokines / immunology* Humans Mice Ubiquitins / immunology* Virus Diseases / immunology* Viruses / immunology* |
| Grant Support | |
ID/Acronym/Agency:
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R01 GM063692-08/GM/NIGMS NIH HHS; //Howard Hughes Medical Institute |
| Chemical | |
Reg. No./Substance:
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0/Cytokines; 0/G1p2 protein, mouse; 0/Ubiquitins; 60267-61-0/ISG15 protein, human |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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