Document Detail


Emerging and Novel Therapeutic Approaches in the Treatment of Male Erectile Dysfunction.
MedLine Citation:
PMID:  21922167     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Over the past few decades, a dramatic increase in our understanding of the pathophysiology of penile erection has occurred. The advent of phosphodiesterase type 5 inhibitors has revolutionized the treatment of erectile dysfunction (ED), while the introduction of modern penile prosthesis has almost completely replaced the need for vascular surgery. Despite the efficacy of current therapeutic options for ED, they are not without limitations and remain insufficient to address the growing patient population and various underlying medical conditions. Newer and novel ED therapies aspire to treat underlying microvascular abnormalities, prevent cavernosal fibrosis, promote endothelial revascularization, modulate neurohormonal pathways, and regenerate new penile tissue.
Authors:
Eric Chung; Gerald B Brock
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-9-16
Journal Detail:
Title:  Current urology reports     Volume:  -     ISSN:  1534-6285     ISO Abbreviation:  -     Publication Date:  2011 Sep 
Date Detail:
Created Date:  2011-9-16     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100900943     Medline TA:  Curr Urol Rep     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
Department of Urology, Princess Alexandra Hospital, Brisbane, QLD, Australia, ericchg@hotmail.com.
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