Document Detail


Emergent percutaneous coronary intervention for resuscitated victims of out-of-hospital cardiac arrest.
MedLine Citation:
PMID:  20049976     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Long-term survival rates even after successful resuscitation from out-of-hospital cardiac arrest are dismal. Most of those initially resuscitated expired during their hospitalization. Recent reports have suggested that a more aggressive approach to postresuscitation care is the key to better outcome. Waiting for the evidence of neurological recovery before acting can result in missed opportunity to improve such recovery. Immediate induction of mild therapeutic hypothermia for all resuscitated victims who remain comatose offers the best hope for neurological recovery. Numerous reports suggest that early coronary angiography and PCI also improve outcome among those resuscitated from cardiac arrest whose postresuscitation ECG show evidence of ST elevation myocardial infarctions. Most promising is combining these two postresuscitation therapies, namely immediate induction of hypothermia and early coronary angiography and PCI. Combining these therapies has resulted in long-term survival rates of 70% with more than 80% of all such survivors neurologically functional. Even those without ST elevation on their postresuscitation ECG can greatly benefit from timely induction of hypothermia and early angiography/PCI.
Authors:
Karl B Kern; Ossama Rahman
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Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions     Volume:  75     ISSN:  1522-726X     ISO Abbreviation:  Catheter Cardiovasc Interv     Publication Date:  2010 Mar 
Date Detail:
Created Date:  2010-03-29     Completed Date:  2010-06-18     Revised Date:  2010-07-02    
Medline Journal Info:
Nlm Unique ID:  100884139     Medline TA:  Catheter Cardiovasc Interv     Country:  United States    
Other Details:
Languages:  eng     Pagination:  616-24     Citation Subset:  IM    
Affiliation:
Sarver Heart Center at the University of Arizona College of Medicine, Tucson, Arizona 85724, USA. kernk@email.arizona.edu
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MeSH Terms
Descriptor/Qualifier:
Adult
Ambulances
Angioplasty, Transluminal, Percutaneous Coronary*
Cardiopulmonary Resuscitation* / instrumentation,  methods
Coma / etiology,  therapy
Combined Modality Therapy
Coronary Angiography
Defibrillators
Electric Countershock / instrumentation
Electrocardiography
Emergency Medical Services*
Female
Heart Arrest / diagnosis,  etiology,  mortality,  therapy*
Hospital Mortality
Humans
Hypothermia, Induced
Male
Middle Aged
Neurologic Examination
Time Factors
Treatment Outcome
Comments/Corrections
Comment In:
Catheter Cardiovasc Interv. 2010 Mar 1;75(4):625   [PMID:  20333661 ]
Catheter Cardiovasc Interv. 2010 Jul 1;76(1):161-3   [PMID:  20578251 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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