Document Detail

Emergency palliation of critical valvular aortic stenosis. A new application of prostaglandin E1.
MedLine Citation:
PMID:  6187209     Owner:  NLM     Status:  MEDLINE    
Prostaglandin E1 (PGE1) was administered by continuous infusion to a critically III 3-day-old infant with severe stenosis of the aortic valve. A beneficial response was evidenced by increases in systemic BP, pulses, perfusion, urinary output, and arterial pH. The infusion of PGE1 improved and stabilized the infant's condition so that cardiac catheterization and surgery could be performed. Successful aortic valvulotomy was performed with continued PGE1 infusion. To out knowledge, this report is the first to describe a patient in whom PGE1 was used successfully for palliation of critical aortic valvular stenosis.
M Artman; R J Boucek; J Hammon; T P Graham
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  American journal of diseases of children (1960)     Volume:  137     ISSN:  0002-922X     ISO Abbreviation:  Am. J. Dis. Child.     Publication Date:  1983 Apr 
Date Detail:
Created Date:  1983-04-15     Completed Date:  1983-04-15     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0370471     Medline TA:  Am J Dis Child     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  339-40     Citation Subset:  AIM; IM    
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MeSH Terms
Aortic Valve Stenosis / congenital,  drug therapy*
Ductus Arteriosus, Patent / drug therapy
Heart Catheterization
Heart Failure / congenital
Infant, Newborn
Palliative Care*
Prostaglandins E / therapeutic use*
Reg. No./Substance:
0/Prostaglandins E

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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