Document Detail


Emergency embolization in the treatment of ruptured hepatocellular carcinoma following transcatheter arterial chemoembolization.
MedLine Citation:
PMID:  20698237     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND/AIMS: Rupture of hepatocellular carcinoma (HCC) following transcatheter arterial chemoembolization (TACE) is a rare and life-threatening complication. The purpose of the present study was to evaluate the utility of emergency embolization for treatment of ruptured HCC following TACE. METHODOLOGY: Five patients developed rupture of tumor after TACE in 1005 patients of HCC from October 2007 to February 2010, and were studied retrospectively. Emergency selective arterial embolization was performed in all 5 patients because of intractable hemorrhage in the peritoneal cavity or around the liver that could not be controlled by conservative method. The mean hemoglobin level before embolization was 75.6 g/L +/- 20.7 (mean +/- standard deviation). RESULTS: Hepatic angiography did not revealed extravasation of contrast from the tumor in all 5 patients with rupture of HCC following TACE. After selective embolization of feeding arteries of the liver tumor, intraperitoneal bleeding from HCC was stopped immediately in all patients. The mean hemoglobin level after embolization in 48 hours was 102.6 g/L +/- 3.5. No severe complication related to emergency embolization was found after treatment. CONCLUSIONS: Emergency arterial embolization is effective for hemostasis of ruptured HCC following TACE in patients with hemodynamically unstable condition.
Authors:
Jun-Hui Sun; Li-Gang Wang; Hai-Wei Bao; Jian-Liang Lou; Li-Xia Cai; Chao Wu; Li-Ming Chen; Shu-Sen Zheng
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Hepato-gastroenterology     Volume:  57     ISSN:  0172-6390     ISO Abbreviation:  Hepatogastroenterology     Publication Date:    2010 May-Jun
Date Detail:
Created Date:  2010-08-11     Completed Date:  2010-09-07     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8007849     Medline TA:  Hepatogastroenterology     Country:  Greece    
Other Details:
Languages:  eng     Pagination:  616-9     Citation Subset:  IM    
Affiliation:
Division of Hepatobiliary and Pancreatic Surgery, Department of Surgery, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou 310003, China.
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Aged, 80 and over
Carcinoma, Hepatocellular / complications,  therapy*
Chemoembolization, Therapeutic / adverse effects*
Embolization, Therapeutic / methods*
Emergencies
Female
Humans
Liver Neoplasms / complications,  therapy*
Male
Middle Aged
Rupture, Spontaneous

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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