Document Detail

Emergency contraception: a review.
MedLine Citation:
PMID:  18283598     Owner:  NLM     Status:  MEDLINE    
Emergency contraception (EC), also known as 'the morning after pill', or post-coital contraception, is a modality of preventing the establishment of a pregnancy after unprotected intercourse. Both a hormonal and an intrauterine form are available. Modern hormonal EC, with low side effects, was first proposed by Yuzpe in 1974. More recently, a new regimen, consisting of levonorgestrel administered alone, was introduced and found in clinical trials to be more effective (if taken as early as possible), and associated with less side effects than the Yuzpe regimen, which it has gradually replaced. The WHO developed another regimen based on the use of the selective progesterone receptor modulator (antiprogestin) mifepristone and conducted trials with different dosages. Intrauterine EC was first proposed by Lippes in 1976. It has the advantage of being applicable for almost a week and the disadvantage of a greater complexity. In addition, this modality is solely interceptive, acting by preventing implantation. Pregnancy rates reported following EC using an intrauterine device with more than 300 mm2 of copper are consistently low (0.1-0.2%).
Carlo Bastianelli; Manuela Farris; G Benagiano
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  The European journal of contraception & reproductive health care : the official journal of the European Society of Contraception     Volume:  13     ISSN:  1362-5187     ISO Abbreviation:  Eur J Contracept Reprod Health Care     Publication Date:  2008 Mar 
Date Detail:
Created Date:  2008-05-19     Completed Date:  2008-07-16     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9712127     Medline TA:  Eur J Contracept Reprod Health Care     Country:  England    
Other Details:
Languages:  eng     Pagination:  9-16     Citation Subset:  IM    
Department of Gynaecologic Sciences, Perinatology and Child Care, University la Sapienza, Rome, Italy.
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MeSH Terms
Contraception, Postcoital / methods*
Contraceptives, Oral, Hormonal*
Drug Interactions
Health Knowledge, Attitudes, Practice
Health Services Accessibility
Intrauterine Devices*
Reg. No./Substance:
0/Contraceptives, Oral, Hormonal

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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